[HTML][HTML] Targeting the holy triangle of quorum sensing, biofilm formation, and antibiotic resistance in pathogenic bacteria

RV Sionov, D Steinberg - Microorganisms, 2022 - mdpi.com
Chronic and recurrent bacterial infections are frequently associated with the formation of
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …

Uncovering the mechanisms of Acinetobacter baumannii virulence

CM Harding, SW Hennon, MF Feldman - Nature Reviews Microbiology, 2018 - nature.com
Acinetobacter baumannii is a nosocomial pathogen that causes ventilator-associated as
well as bloodstream infections in critically ill patients, and the spread of multidrug-resistant …

Polymyxins: antibacterial activity, susceptibility testing, and resistance mechanisms encoded by plasmids or chromosomes

L Poirel, A Jayol, P Nordmann - Clinical microbiology reviews, 2017 - Am Soc Microbiol
Polymyxins are well-established antibiotics that have recently regained significant interest
as a consequence of the increasing incidence of infections due to multidrug-resistant Gram …

[HTML][HTML] Biology of Acinetobacter baumannii: Pathogenesis, Antibiotic Resistance Mechanisms, and Prospective Treatment Options

CR Lee, JH Lee, M Park, KS Park, IK Bae… - Frontiers in cellular …, 2017 - frontiersin.org
Acinetobacter baumannii is undoubtedly one of the most successful pathogens responsible
for hospital-acquired nosocomial infections in the modern healthcare system. Due to the …

Towards understanding MCR-like colistin resistance

J Sun, H Zhang, YH Liu, Y Feng - Trends in microbiology, 2018 - cell.com
Antibiotic resistance has become a global public health priority. Polymyxins, a family of
cationic polypeptide antibiotics, act as a final line of refuge against severe infections by …

Molecular mechanisms of antibiotic resistance

JMA Blair, MA Webber, AJ Baylay, DO Ogbolu… - Nature reviews …, 2015 - nature.com
Antibiotic-resistant bacteria that are difficult or impossible to treat are becoming increasingly
common and are causing a global health crisis. Antibiotic resistance is encoded by several …

[HTML][HTML] Acinetobacter baumannii Resistance: A Real Challenge for Clinicians

R Vázquez-López, SG Solano-Gálvez… - Antibiotics, 2020 - mdpi.com
Acinetobacter baumannii (named in honor of the American bacteriologists Paul and Linda
Baumann) is a Gram-negative, multidrug-resistant (MDR) pathogen that causes nosocomial …

[HTML][HTML] Mechanisms of polymyxin resistance: acquired and intrinsic resistance in bacteria

AO Olaitan, S Morand, JM Rolain - Frontiers in microbiology, 2014 - frontiersin.org
Polymyxins are polycationic antimicrobial peptides that are currently the last-resort
antibiotics for the treatment of multidrug-resistant, Gram-negative bacterial infections. The …

Emerging broad-spectrum resistance in Pseudomonas aeruginosa and Acinetobacter baumannii: mechanisms and epidemiology

A Potron, L Poirel, P Nordmann - International journal of antimicrobial …, 2015 - Elsevier
Multidrug resistance is quite common among non-fermenting Gram-negative rods, in
particular among clinically relevant species including Pseudomonas aeruginosa and …

Permeability barrier of Gram-negative cell envelopes and approaches to bypass it

HI Zgurskaya, CA López… - ACS infectious diseases, 2015 - ACS Publications
Gram-negative bacteria are intrinsically resistant to many antibiotics. Species that have
acquired multidrug resistance and cause infections that are effectively untreatable present a …