Genotypic resistance testing of HIV-1 DNA in peripheral blood mononuclear cells
C Chu, D Armenia, C Walworth… - Clinical Microbiology …, 2022 - Am Soc Microbiol
SUMMARY HIV-1 DNA exists in nonintegrated linear and circular episomal forms and as
integrated proviruses. In patients with plasma viremia, most peripheral blood mononuclear …
integrated proviruses. In patients with plasma viremia, most peripheral blood mononuclear …
Persistent low-level viremia in persons living with HIV undertreatment: an unresolved status
C Crespo-Bermejo, ER de Arellano, V Lara-Aguilar… - Virulence, 2021 - Taylor & Francis
Antiretroviral therapy (ART) allows suppressed viremia to reach less than 50 copies/mL in
most treated persons living with HIV (PLWH). However, the existence of PLWH that show …
most treated persons living with HIV (PLWH). However, the existence of PLWH that show …
[HTML][HTML] Impact of low-level viremia with drug resistance on CD4 cell counts among people living with HIV on antiretroviral treatment in China
P Liu, Y You, L Liao, Y Feng, Y Shao, H Xing… - BMC Infectious …, 2022 - Springer
Abstract Background Maintaining plasma HIV RNA suppression below the limit of
quantification is the goal of antiretroviral therapy (ART). When viral loads (VL) remain in low …
quantification is the goal of antiretroviral therapy (ART). When viral loads (VL) remain in low …
[HTML][HTML] HIV: how to manage low-level viraemia in people living with HIV
EK Hanners, J Benitez-Burke, ME Badowski - Drugs in Context, 2022 - ncbi.nlm.nih.gov
Background People living with HIV (PLWH) and receiving antiretroviral therapy (ART) have
a goal of achieving and maintaining viral suppression; however, low-level viraemia …
a goal of achieving and maintaining viral suppression; however, low-level viraemia …
Low‐level HIV viraemia during antiretroviral therapy: Longitudinal patterns and predictors of viral suppression
Objectives Our objective was to characterize longitudinal patterns of viraemia and factors
associated with viral suppression in people with HIV and low‐level viraemia (LLV) during …
associated with viral suppression in people with HIV and low‐level viraemia (LLV) during …
Extensive drug resistance during low-level HIV viraemia while taking NNRTI-based ART supports lowering the viral load threshold for regimen switch in resource …
JA Brown, A Amstutz, BL Nsakala… - Journal of …, 2021 - academic.oup.com
Objectives WHO guidelines on ART define the HIV-1 viral load (VL) threshold for treatment
failure at 1000 copies/mL. The Switch Either near Suppression Or THOusand (SESOTHO) …
failure at 1000 copies/mL. The Switch Either near Suppression Or THOusand (SESOTHO) …
The suboptimal pediatric HIV viral load cascade: multidistrict cohort study among children taking antiretroviral therapy in Lesotho, Southern Africa
JA Muhairwe, JA Brown, L Motaboli… - The Pediatric …, 2022 - journals.lww.com
Background: Children living with HIV and taking antiretroviral therapy (ART) are a priority
group for routine viral load (VL) monitoring. As per Lesotho guidelines, a VL≥ 1000 …
group for routine viral load (VL) monitoring. As per Lesotho guidelines, a VL≥ 1000 …
[HTML][HTML] The impact of gender and the social determinants of health on the clinical course of people living with HIV in Myanmar: an observational study
Background There is a growing recognition of the impact of gender and the social
determinants of health on the clinical course of people living with HIV (PLHIV). However, the …
determinants of health on the clinical course of people living with HIV (PLHIV). However, the …
Feasibility and clinical relevance of HIV-1 drug resistance testing in patients with low-level viraemia in South Africa
A Bangalee, L Hans, K Steegen - Journal of Antimicrobial …, 2021 - academic.oup.com
Objectives To determine the feasibility of HIV genotyping at low-level viraemia (LLV) using
an in-house assay in a South African population and the prevalence, as well as the clinical …
an in-house assay in a South African population and the prevalence, as well as the clinical …
Non-suppressible viraemia during HIV-1 therapy: a challenge for clinicians
A Esteban-Cantos, R Montejano, A Pinto-Martínez… - The Lancet …, 2024 - thelancet.com
In individuals receiving antiretroviral therapy (ART), persistent low-level viraemia not
attributed to suboptimal ART adherence, detrimental pharmacological interactions, or drug …
attributed to suboptimal ART adherence, detrimental pharmacological interactions, or drug …