Genotypic resistance testing of HIV-1 DNA in peripheral blood mononuclear cells

C Chu, D Armenia, C Walworth… - Clinical Microbiology …, 2022 - Am Soc Microbiol
SUMMARY HIV-1 DNA exists in nonintegrated linear and circular episomal forms and as
integrated proviruses. In patients with plasma viremia, most peripheral blood mononuclear …

Persistent low-level viremia in persons living with HIV undertreatment: an unresolved status

C Crespo-Bermejo, ER de Arellano, V Lara-Aguilar… - Virulence, 2021 - Taylor & Francis
Antiretroviral therapy (ART) allows suppressed viremia to reach less than 50 copies/mL in
most treated persons living with HIV (PLWH). However, the existence of PLWH that show …

[HTML][HTML] Impact of low-level viremia with drug resistance on CD4 cell counts among people living with HIV on antiretroviral treatment in China

P Liu, Y You, L Liao, Y Feng, Y Shao, H Xing… - BMC Infectious …, 2022 - Springer
Abstract Background Maintaining plasma HIV RNA suppression below the limit of
quantification is the goal of antiretroviral therapy (ART). When viral loads (VL) remain in low …

[HTML][HTML] HIV: how to manage low-level viraemia in people living with HIV

EK Hanners, J Benitez-Burke, ME Badowski - Drugs in Context, 2022 - ncbi.nlm.nih.gov
Background People living with HIV (PLWH) and receiving antiretroviral therapy (ART) have
a goal of achieving and maintaining viral suppression; however, low-level viraemia …

Low‐level HIV viraemia during antiretroviral therapy: Longitudinal patterns and predictors of viral suppression

S Elén, P Björkman, M Zazzi, M Böhm, E Bernal… - HIV …, 2024 - Wiley Online Library
Objectives Our objective was to characterize longitudinal patterns of viraemia and factors
associated with viral suppression in people with HIV and low‐level viraemia (LLV) during …

Extensive drug resistance during low-level HIV viraemia while taking NNRTI-based ART supports lowering the viral load threshold for regimen switch in resource …

JA Brown, A Amstutz, BL Nsakala… - Journal of …, 2021 - academic.oup.com
Objectives WHO guidelines on ART define the HIV-1 viral load (VL) threshold for treatment
failure at 1000 copies/mL. The Switch Either near Suppression Or THOusand (SESOTHO) …

The suboptimal pediatric HIV viral load cascade: multidistrict cohort study among children taking antiretroviral therapy in Lesotho, Southern Africa

JA Muhairwe, JA Brown, L Motaboli… - The Pediatric …, 2022 - journals.lww.com
Background: Children living with HIV and taking antiretroviral therapy (ART) are a priority
group for routine viral load (VL) monitoring. As per Lesotho guidelines, a VL≥ 1000 …

[HTML][HTML] The impact of gender and the social determinants of health on the clinical course of people living with HIV in Myanmar: an observational study

PP Nyein, E Aung, NM Aung, MM Kyi, M Boyd… - AIDS Research and …, 2021 - Springer
Background There is a growing recognition of the impact of gender and the social
determinants of health on the clinical course of people living with HIV (PLHIV). However, the …

Feasibility and clinical relevance of HIV-1 drug resistance testing in patients with low-level viraemia in South Africa

A Bangalee, L Hans, K Steegen - Journal of Antimicrobial …, 2021 - academic.oup.com
Objectives To determine the feasibility of HIV genotyping at low-level viraemia (LLV) using
an in-house assay in a South African population and the prevalence, as well as the clinical …

Non-suppressible viraemia during HIV-1 therapy: a challenge for clinicians

A Esteban-Cantos, R Montejano, A Pinto-Martínez… - The Lancet …, 2024 - thelancet.com
In individuals receiving antiretroviral therapy (ART), persistent low-level viraemia not
attributed to suboptimal ART adherence, detrimental pharmacological interactions, or drug …