Protein corona: a new approach for nanomedicine design

VH Nguyen, BJ Lee - International journal of nanomedicine, 2017 - Taylor & Francis
After administration of nanoparticle (NP) into biological fluids, an NP–protein complex is
formed, which represents the “true identity” of NP in our body. Hence, protein–NP interaction …

The protein corona and its effects on nanoparticle-based drug delivery systems

H Li, Y Wang, Q Tang, D Yin, C Tang, E He, L Zou… - Acta biomaterialia, 2021 - Elsevier
In most cases, once nanoparticles (NPs) enter the blood, their surface is covered by
biological molecules, especially proteins, forming a so-called protein corona (PC). As a …

Strategic role of selected noble metal nanoparticles in medicine

M Rai, AP Ingle, S Birla, A Yadav… - Critical reviews in …, 2016 - Taylor & Francis
Noble metals and their compounds have been used as therapeutic agents from the ancient
time in medicine for the treatment of various infections. Recently, much progress has been …

Exploration of zinc oxide nanoparticles as a multitarget and multifunctional anticancer nanomedicine

J Wang, JS Lee, D Kim, L Zhu - ACS applied materials & interfaces, 2017 - ACS Publications
Because of the complexity of cancer, an ideal anticancer strategy is better to target both
cancer cells and the tumor microenvironment. In this study, for the first time, we …

Aggregation effects on the magnetic properties of iron oxide colloids

L Gutiérrez, L De la Cueva, M Moros, E Mazarío… - …, 2019 - iopscience.iop.org
Magnetic nanoparticles (MNPs), and in particular iron oxide nanoparticles (mainly magnetite
and maghemite), are being widely used in the form of aqueous colloids for biomedical …

The nano-plasma interface: Implications of the protein corona

J Wolfram, Y Yang, J Shen, A Moten, C Chen… - Colloids and Surfaces B …, 2014 - Elsevier
The interactions between nanoparticles and macromolecules in the blood plasma dictate the
biocompatibility and efficacy of nanotherapeutics. Accordingly, the properties of …

In-vitro in-vivo correlation (IVIVC) in nanomedicine: Is protein corona the missing link?

P Jain, RS Pawar, RS Pandey, J Madan, S Pawar… - Biotechnology …, 2017 - Elsevier
One of the unmet challenges in nanotechnology is to understand and establish the
relationship between physicochemical properties of nanoparticles (NPs) and its biological …

Effect of zinc oxide nanomaterials-induced oxidative stress on the p53 pathway

MI Setyawati, CY Tay, DT Leong - Biomaterials, 2013 - Elsevier
Excessive production of reactive oxygen species (ROS) is a hallmark feature in
nanomaterials (NMs) induced cellular toxicity. However, the inter-relationship between NMs …

Zinc oxide nanoparticles induce necrosis and apoptosis in macrophages in a p47phox-and Nrf2-independent manner

V Wilhelmi, U Fischer, H Weighardt, K Schulze-Osthoff… - PloS one, 2013 - journals.plos.org
In view of the steadily increasing use of zinc oxide nanoparticles in various industrial and
consumer applications, toxicological investigations to evaluate their safety are highly …

Nanocellulose hybrids with metal oxides nanoparticles for biomedical applications

M Oprea, DM Panaitescu - Molecules, 2020 - mdpi.com
Cellulose is one of the most affordable, sustainable and renewable resources, and has
attracted much attention especially in the form of nanocellulose. Bacterial cellulose …