Cancer is one of the leading causes of death around the world and although the different
clinical approaches have helped to increase survival rates, incidence is still high and so its …

Apoptotic cell death generally characterized by a morphologically homogenous entity has
been considered to be essentially non-immunogenic. However, apoptotic cancer cell death …

Recently, intelligent packaging has emerged for monitoring food quality in food industry.
This study aimed to develop the electrospun HACC/PCL/SKN nanofibrous films with …

Natural colorants (anthocyanin and shikonin) were blended in different ratios (3: 1 and 1: 3)
and used for the preparation of carboxymethyl cellulose (CMC)/agar-based functional …

Phytochemicals gained considerable interest during the past years as source to develop
new treatment options for chemoprevention and cancer therapy. Motivated by the fact that a …

The immunogenicity of malignant cells has recently been acknowledged as a critical
determinant of efficacy in cancer therapy. Thus, besides developing direct …

We recently reported that shikonin and its analogs were a class of necroptotic inducers that
could bypass cancer drug resistance. However, the molecular targets of shikonin are not …

Chronic kidney diseases generally lead to renal fibrosis. Despite great progress having
been made in identifying molecular mediators of fibrosis, the mechanism that governs renal …

The naphthoquinone shikonin is the main active principle of Zicao, a traditional Chinese
herbal medicine made from the dried root of Lithospermum erythrorhizon. Studies carried …

Multifunctional carboxymethyl cellulose/agar-based smart films were fabricated combining
cellulose nanocrystals (CNC) separated from onion peel and shikonin isolated from the …