The brain is unique among organs in many respects, including its mechanisms of lipid
synthesis and energy production. The nervous system-specific metabolite N-acetylaspartate …

" For three decades psychiatrists have turned to Lishman's Organic Psychiatry as the
standard neuropsychiatry reference. It stood as the last great single author reference text in …

Objective: To determine whether cognitive impairment and brain injury as measured by
proton magnetic resonance spectroscopy (MRS) persist in the setting of HAART. Design …

OBJECTIVE: The authors examined the separate and combined effects of
methamphetamine dependence and HIV infection on brain morphology. METHOD …

This study aims to determine the relationship among cerebral metabolite concentrations (on
proton magnetic resonance spectroscopy or 1H MRS), cognitive function, and clinical …

Objective: Differences in diagnostic criteria and methods have led to mixed results regarding
the metabolite pattern of HIV-associated brain injury in relation to neurocognitive …

Scanner-to-scanner variability of activation in multicenter fMRI studies is often considered
undesirable. The purpose of this investigation was to evaluate the effect of a new …

Objective Single voxel proton magnetic resonance spectroscopy (MRS) can be used to
monitor changes in brain inflammation and neuronal integrity associated with HIV infection …

Nucleoside reverse transcriptase inhibitors (NRTIs) suppress human immunodeficiency
virus (HIV) replication, but are often associated with mitochondrial toxicity. Although well …

N-Acetylaspartate (NAA) and its derivative, N-acetylaspartylglutamate (NAAG), are
synthesized in neurons and present in very high concentrations in the CNS. NAA is a marker …