Redefining the components of central CO2 chemosensitivity – towards a better understanding of mechanism
RTR Huckstepp, N Dale - The Journal of physiology, 2011 - Wiley Online Library
The field of CO2 chemosensitivity has developed considerably in recent years. There has
been a mounting number of competing nuclei proposed as chemosensitive along with an …
been a mounting number of competing nuclei proposed as chemosensitive along with an …
Developmental origin of preBötzinger complex respiratory neurons
A subset of preBötzinger Complex (preBötC) neurokinin 1 receptor (NK1R) and somatostatin
peptide (SST)-expressing neurons are necessary for breathing in adult rats, in vivo. Their …
peptide (SST)-expressing neurons are necessary for breathing in adult rats, in vivo. Their …
Prevention of seizure-induced sudden death in a chronic SUDEP model by semichronic administration of a selective serotonin reuptake inhibitor
CL Faingold, S Tupal, M Randall - Epilepsy & Behavior, 2011 - Elsevier
DBA/1 mice are a chronically susceptible model of sudden unexpected death in epilepsy
(SUDEP) that exhibit chronic audiogenic generalized convulsive seizures (GCSs), leading to …
(SUDEP) that exhibit chronic audiogenic generalized convulsive seizures (GCSs), leading to …
Development of respiratory control: evolving concepts and perspectives
C Gaultier, J Gallego - Respiratory physiology & neurobiology, 2005 - Elsevier
The mechanisms underlying respiratory system immaturity in newborns have been
investigated, both in vivo and in vitro, in humans and in animals. Immaturity affects breathing …
investigated, both in vivo and in vitro, in humans and in animals. Immaturity affects breathing …
Abnormal serotonin receptor expression in DBA/2 mice associated with susceptibility to sudden death due to respiratory arrest
VV Uteshev, S Tupal, Y Mhaskar, CL Faingold - Epilepsy research, 2010 - Elsevier
Previous studies indicate that DBA/2 mice may be a useful model of human sudden
unexpected death in epilepsy (SUDEP), since these mice exhibit generalized convulsive …
unexpected death in epilepsy (SUDEP), since these mice exhibit generalized convulsive …
Maintenance of gasping and restoration of eupnea after hypoxia is impaired following blockers of α1-adrenergic receptors and serotonin 5-HT2 receptors
WM St.-John, JC Leiter - Journal of Applied Physiology, 2008 - journals.physiology.org
In severe hypoxia or ischemia, normal eupneic breathing fails and is replaced by gasping.
Gasping serves as part of a process of autoresuscitation by which eupnea is reestablished …
Gasping serves as part of a process of autoresuscitation by which eupnea is reestablished …
Persistence of eupnea and gasping following blockade of both serotonin type 1 and 2 receptors in the in situ juvenile rat preparation
VAL Toppin, MB Harris, AM Kober… - Journal of applied …, 2007 - journals.physiology.org
In severe hypoxia or ischemia, normal eupneic breathing is replaced by gasping, which can
serve as a powerful mechanism for “autoresuscitation.” We have proposed that gasping is …
serve as a powerful mechanism for “autoresuscitation.” We have proposed that gasping is …
Serotonin-induced in vitro long-term facilitation exhibits differential pattern sensitivity in cervical and thoracic inspiratory motor output
MR Lovett-Barr, GS Mitchell, I Satriotomo, SM Johnson - Neuroscience, 2006 - Elsevier
Intermittent hypoxia induces 5-HT-dependent, pattern-sensitive long-term facilitation (LTF) of
spinal respiratory motor output. We used a split-bath in vitro neonatal rat brainstem–spinal …
spinal respiratory motor output. We used a split-bath in vitro neonatal rat brainstem–spinal …
Peripheral neuroplasticity of respiratory chemoreflexes, induced by prenatal nicotinic exposure: Implication for SIDS
F Xu, L Zhao, J Zhuang, X Gao - Respiratory Physiology & Neurobiology, 2023 - Elsevier
Abstract Sudden Infant Death Syndrome (SIDS) occurs during sleep in seemingly healthy
infants. Maternal cigarette smoking and hypoxemia during sleep are assumed to be the …
infants. Maternal cigarette smoking and hypoxemia during sleep are assumed to be the …
Diencephalic and mesencephalic influences on ponto-medullary respiratory control in normoxic and hypoxic conditions: an in vitro study on central nervous system …
N Voituron, A Frugiere, F Gros, JM Macron, L Bodineau - Neuroscience, 2005 - Elsevier
We investigated the effects of the diencephalon and mesencephalon on the central
respiratory drive originating from ponto-medullary regions in normoxic and hypoxic …
respiratory drive originating from ponto-medullary regions in normoxic and hypoxic …