Cognitive dysfunction in unipolar depression: implications for treatment
MH Trivedi, TL Greer - Journal of affective disorders, 2014 - Elsevier
Objective The primary objective of this review is to examine the literature assessing
abnormalities in neural circuitry and cognition early in the course of major depressive …
abnormalities in neural circuitry and cognition early in the course of major depressive …
Relationship between sleep disturbance and depression, anxiety, and functioning in college students
M Nyer, A Farabaugh, K Fehling, D Soskin… - Depression and …, 2013 - Wiley Online Library
Background Sleep disturbance (SD) has complex associations with depression, both
preceding and following the onset and recurrence of depression. We hypothesized that …
preceding and following the onset and recurrence of depression. We hypothesized that …
A randomized proof-of-mechanism trial applying the 'fast-fail'approach to evaluating κ-opioid antagonism as a treatment for anhedonia
Abstract The National Institute of Mental Health (NIMH)'fast-fail'approach seeks to improve
too-often-misleading early-phase drug development methods by incorporating biomarker …
too-often-misleading early-phase drug development methods by incorporating biomarker …
Combining medications to enhance depression outcomes (CO-MED): acute and long-term outcomes of a single-blind randomized study
AJ Rush, MH Trivedi, JW Stewart… - American Journal of …, 2011 - Am Psychiatric Assoc
Objective: Two antidepressant medication combinations were compared with selective
serotonin reuptake inhibitor monotherapy to determine whether either combination …
serotonin reuptake inhibitor monotherapy to determine whether either combination …
Cognitive dysfunction in major depressive disorder: a state-of-the-art clinical review
B Bortolato, A F. Carvalho… - CNS & Neurological …, 2014 - benthamdirect.com
Major depressive disorder (MDD) is a prevalent and recurring mental disorder often
associated with high rates of non-recovery and substantial consequences on psychosocial …
associated with high rates of non-recovery and substantial consequences on psychosocial …
Daily electronic self-monitoring in bipolar disorder using smartphones–the MONARCA I trial: a randomized, placebo-controlled, single-blind, parallel group trial
BackgroundThe number of studies on electronic self-monitoring in affective disorder and
other psychiatric disorders is increasing and indicates high patient acceptance and …
other psychiatric disorders is increasing and indicates high patient acceptance and …
Discrete neurocognitive subgroups in fully or partially remitted bipolar disorder: associations with functional abilities
Background Neurocognitive impairment in remitted patients with bipolar disorder contributes
to functional disabilities. However, the pattern and impact of these deficits are unclear …
to functional disabilities. However, the pattern and impact of these deficits are unclear …
Cognitive symptoms in patients with major depressive disorder and their implications for clinical practice
GI Papakostas - The Journal of clinical psychiatry, 2013 - psychiatrist.com
Context: The literature regarding cognitive symptoms in major depressive disorder (MDD) is
vast and often contradictory. To provide clinicians with a concise understanding of these …
vast and often contradictory. To provide clinicians with a concise understanding of these …
Clinical relevance of fatigue as a residual symptom in major depressive disorder
Residual symptoms of major depressive disorder (MDD) following treatment are increasingly
recognized as having a negative impact on the patient because of their association with lack …
recognized as having a negative impact on the patient because of their association with lack …
Screening for cognitive dysfunction in unipolar depression: validation and evaluation of objective and subjective tools
Background Persistent cognitive dysfunction in unipolar depression (UD) contributes to
socio-occupational impairment, but there are no feasible methods to screen for and monitor …
socio-occupational impairment, but there are no feasible methods to screen for and monitor …