Platelets play a central role in arrest of bleeding. The ability of platelets to engage with
extracellular matrix proteins of the subendothelium has long been recognised as a pivotal …

GPVI and CLEC-2 have emerged as promising targets for long-term prevention of both
arterial thrombosis and thrombo-inflammation with a decreased bleeding risk relative to …

Ischemic stroke is a major type of stroke worldwide currently without effective treatment,
although antiplatelet therapy is an existing option for it. In previous studies, heat shock …

Acute coronary syndromes (ACS) are a global cause of mortality and morbidity that affect
millions of lives worldwide. Following atherosclerotic plaque rupture, platelet activation and …

Diindolylmethane (DIM), a major metabolite of indole-3-carbinol (I3C), plays a vital role in
the pharmacological actions of I3C. The role of DIM in the inhibition of platelet aggregation …

Nutritional availability during fasting and refeeding affects the temporal redistribution of
lymphoid and myeloid immune cells among the circulating and tissue‐resident pools …

Two novel anti-thrombotic diastereomers S007–867 and S007–1175 had been recently
identified by CSIR-CDRI. We performed extensive experimental solid-form screening studies …

Thrombosis is a major contributor to the pathophysiology of cardiovascular diseases. The
involvement of platelets in the formation of thrombus has been studied extensively. Platelet …

Cardiovascular disease, including myocardial infarction, remains the number one cause of
worldwide morbidity and mortality. The major cause of myocardial infarction is arterial …

Impaired glucose metabolism is associated with chronic inflammation, aberrant immunity
and anomalous leukocyte trafficking. Conversely, infusion of functional immune cells …