Recent insights into the biomarkers, molecular targets and mechanisms of non-alcoholic steatohepatitis-driven hepatocarcinogenesis

A Kakehashi, S Suzuki, H Wanibuchi - Cancers, 2023 - mdpi.com
Simple Summary This review is focused on the research recently published in the field of
non-alcoholic fatty liver disease (NAFLD) or metabolic dysfunction-associated steatotic liver …

Anti-obesogenic effects of plant natural products: A focus on Korean traditional foods

G Das, LAJ Ortega, S Gonçalves, JB Heredia… - Trends in Food Science …, 2024 - Elsevier
Background Natural products from food products can play an important role in obesity
management. Korean traditional food (KTF), characterized by a high inclusion of fresh or …

Maternal and paternal obesity differentially reprogram the ovarian mitochondrial biogenesis of F1 female rats

AG Ramadan, WM Abdel-Rehim, RA El-Tahan… - Scientific Reports, 2023 - nature.com
Obesity has harmful consequences on reproductive outcomes and the rapid increase in
obesity is assumed to be influenced by epigenetics and trans-generation effects. Our study …

[HTML][HTML] Pharmacological effects of mTORC1/C2 inhibitor in a preclinical model of NASH progression

M Arora, Z Pavlíková, T Kučera, P Kozlík… - Biomedicine & …, 2023 - Elsevier
Abstract Knowledge of the benefits of mTOR inhibition concerning adipogenesis and
inflammation has recently encouraged the investigation of a new generation of mTOR …

Nutritional Strategies against Diabetic Nephropathy: Insights from Animal Studies and Human Trials

J Zhou, N Franceschini, WHD Townley-Tilson… - Nutrients, 2024 - mdpi.com
Diabetic nephropathy (DN), defined as continuously elevated urinary albumin and a
diminished estimated glomerular filtration rate, is a serious complication of both type 1 …

A narrative review on the mechanism of natural flavonoids in improving glucolipid metabolism disorders

W Niu, Y Feng, M Peng, J Cai - Phytotherapy Research, 2024 - Wiley Online Library
Glucolipid metabolism disorder (GLMD) is a complex chronic disease characterized by
glucose and lipid metabolism disorders with a complex and diverse etiology and rapidly …

Exploring the Prospective Role of Propolis in Modifying Aging Hallmarks

C Scorza, V Goncalves, J Finsterer, F Scorza… - Cells, 2024 - mdpi.com
Aging populations worldwide are placing age-related diseases at the forefront of the
research agenda. The therapeutic potential of natural substances, especially propolis and its …

Phytic acid-based nanomedicine against mTOR represses lipogenesis and immune response for metabolic dysfunction-associated steatohepatitis therapy

F Xu, S Zhao, Y Zhu, J Zhu, L Kong, H Li, S Ma… - Life …, 2024 - academic.oup.com
Metabolic dysfunction-associated steatohepatitis (MASH) is one of the most common chronic
liver diseases and is mainly caused by metabolic disorders and systemic inflammatory …

[PDF][PDF] Chrysin's dose-dependent effects on steroidogenesis in female BALB/c mice: In vivo study of adrenal, ovarian, and uterine hormone regulation

KM Alqaisi, MA Abbas, R Alshawawreh - Pharmacia, 2024 - pharmacia.pensoft.net
Background: Chrysin is known for its pharmacological effects and structural resemblance to
estrogen. The study explores the impact of chrysin on steroidogenesis focusing on adrenal …

Ketogenic diet and beta-hydroxybutyrate modulate the hepatic expression of AKT/PI3K/mTOR pathway during treatment of obesity in rats.

W Salim, M Kamel, M Helmy… - Journal of the Medical …, 2024 - jmalexu.journals.ekb.eg
The ketogenic diet (KD) is a dietary plan enriched in fat and lower in carbohydrates
designed to treat obesity through boost the production and consumption of ketone bodies …