Retinoblastoma

H Dimaras, TW Corson, D Cobrinik, A White… - Nature reviews Disease …, 2015 - nature.com
Retinoblastoma is a rare cancer of the infant retina that is diagnosed in approximately 8,000
children each year worldwide. It forms when both retinoblastoma gene (RB1) alleles are …

Conservative management of retinoblastoma: Challenging orthodoxy without compromising the state of metastatic grace.“Alive, with good vision and no comorbidity”

FL Munier, M Beck-Popovic, GL Chantada… - Progress in retinal and …, 2019 - Elsevier
Retinoblastoma is lethal by metastasis if left untreated, so the primary goal of therapy is to
preserve life, with ocular survival, visual preservation and quality of life as secondary aims …

[HTML][HTML] Inhibition of MMP-2 and MMP-9 decreases cellular migration, and angiogenesis in in vitro models of retinoblastoma

AH Webb, BT Gao, ZK Goldsmith, AS Irvine, N Saleh… - BMC cancer, 2017 - Springer
Abstract Background Retinoblastoma (Rb) is the most common primary intraocular tumor in
children. Local treatment of the intraocular disease is usually effective if diagnosed early; …

The epidemiological challenge of the most frequent eye cancer: retinoblastoma, an issue of birth and death

T Kivelä - British Journal of Ophthalmology, 2009 - bjo.bmj.com
Many papers on retinoblastoma open with a statement that it is the most common primary
intraocular cancer in children and a rare disease. True enough. After reflecting a little longer …

The clinically used photosensitizer Verteporfin (VP) inhibits YAP-TEAD and human retinoblastoma cell growth in vitro without light activation

K Brodowska, A Al-Moujahed, A Marmalidou… - Experimental eye …, 2014 - Elsevier
Verteporfin (VP), a benzoporphyrin derivative, is clinically used in photodynamic therapy for
neovascular macular degeneration. Recent studies indicate that VP may inhibit growth of …

Pediatric eye evaluations preferred practice pattern®: I. Vision screening in the primary care and community setting; II. Comprehensive ophthalmic examination

DK Wallace, CL Morse, M Melia, DT Sprunger… - …, 2018 - aaojournal.org
Vision screening for children is an evaluation to detect reduced visual acuity or risk factors
that threaten the healthy growth and development of the eye and visual system. Vision …

Retinoblastoma

MV Ortiz, IJ Dunkel - Journal of child neurology, 2016 - journals.sagepub.com
Retinoblastoma is the most common primary intraocular malignancy of childhood. It typically
presents with leukocoria or strabismus. In later stages of the disease, the child may exhibit …

[HTML][HTML] Screening children at risk for retinoblastoma: consensus report from the American Association of Ophthalmic Oncologists and Pathologists

AH Skalet, DS Gombos, BL Gallie, JW Kim, CL Shields… - Ophthalmology, 2018 - Elsevier
Purpose To provide a set of surveillance guidelines for children at risk for development of
retinoblastoma. Design Consensus panel. Participants Expert panel of ophthalmic …

Clinical presentation and survival of retinoblastoma in Indian children

B Chawla, F Hasan, R Azad, R Seth… - British Journal of …, 2016 - bjo.bmj.com
Objective To study the clinical presentation and survival among Indian children with
retinoblastoma (RB) and to determine factors predictive of poor outcome. Methods A …

Retinoblastoma

DR Lohmann, BL Gallie - e LS, 2001 - Wiley Online Library
Retinoblastoma is a malignant tumor that originates from the developing retina. Mutations in
both alleles of the retinoblastoma gene are a prerequisite for the development of this tumor …