Polymorphism in cocrystals: a review and assessment of its significance
Cocrystals have gained much interest in recent years owing to their potential to improve the
physicochemical properties of the parent compounds. It was once thought that cocrystals …
physicochemical properties of the parent compounds. It was once thought that cocrystals …
Niclosamide repositioning for treating cancer: Challenges and nano-based drug delivery opportunities
Drug repositioning may be defined as a process when new biological effects for known
drugs are identified, leading to recommendations for new therapeutic applications …
drugs are identified, leading to recommendations for new therapeutic applications …
[图书][B] Handbook of aqueous solubility data
SH Yalkowsky, Y He, P Jain - 2016 - books.google.com
The second edition of this landmark volume continues the tradition of providing an extensive
compilation of published aqueous solubility data for a wide variety of organic nonelectrolytes …
compilation of published aqueous solubility data for a wide variety of organic nonelectrolytes …
Trends in solubility of polymorphs
M Pudipeddi, ATM Serajuddin - Journal of pharmaceutical sciences, 2005 - Elsevier
Polymorphism of drug substances has been the subject of intense investigation in the
pharmaceutical field for over 40 years. Considering the multitude of reports on solubility or …
pharmaceutical field for over 40 years. Considering the multitude of reports on solubility or …
Phase transition enthalpy measurements of organic and organometallic compounds and ionic liquids. Sublimation, vaporization, and fusion enthalpies from 1880 to …
W Acree, JS Chickos - Journal of Physical and Chemical Reference …, 2017 - pubs.aip.org
This compendium completes a previous report published in 2016 [2016ACR/CHI] on phase
change enthalpies. Paper I of this compendium includes over 6600 organic compounds …
change enthalpies. Paper I of this compendium includes over 6600 organic compounds …
Quality by design steered development of Niclosamide loaded liposomal thermogel for Melanoma: In vitro and Ex vivo evaluation
Melanoma is the most malignant form of skin cancer across the globe. Conventional
therapies are currently ineffective which could be attributed to the rampant chemo …
therapies are currently ineffective which could be attributed to the rampant chemo …
[PDF][PDF] 杀螺药物氯硝柳胺研究进展
邢云天， 戴建荣 - 中国血吸虫病防治杂志, 2010 - zgxfzz.com
杀螺药物氯硝柳胺研究进展 Page 1 [文章编号] 10056661(2010)05050405 ·综述· 杀螺
药物氯硝柳胺研究进展 邢云天(综述),戴建荣'(审校) [摘要] 氯硝柳胺是世界卫生组织唯一推荐 …
药物氯硝柳胺研究进展 邢云天(综述),戴建荣'(审校) [摘要] 氯硝柳胺是世界卫生组织唯一推荐 …
Comparison of the aqueous solubilization of practically insoluble niclosamide by polyamidoamine (PAMAM) dendrimers and cyclodextrins
This study is the first report of the solubilization of niclosamide by cyclodextrin complexation
or the interaction between the drug and polyamidoamine (PAMAM) dendrimers. Half …
or the interaction between the drug and polyamidoamine (PAMAM) dendrimers. Half …
Pharmaceutical cocrystals of niclosamide
Niclosamide (NCL) is an anthelmintic BCS class II drug of low solubility and high
permeability. Pharmaceutical cocrystals of NCL were prepared with GRAS molecules, such …
permeability. Pharmaceutical cocrystals of NCL were prepared with GRAS molecules, such …
Amorphous solid dispersions and the contribution of nanoparticles to in vitro dissolution and in vivo testing: Niclosamide as a case study
We developed an amorphous solid dispersion (ASD) of the poorly water-soluble molecule
niclosamide that achieved a more than two-fold increase in bioavailability. Notably, this …
niclosamide that achieved a more than two-fold increase in bioavailability. Notably, this …