Gestational trophoblastic disease

MJ Seckl, NJ Sebire, RS Berkowitz - The Lancet, 2010 - thelancet.com
Gestational trophoblastic disease encompasses a range of pregnancy-related disorders,
consisting of the premalignant disorders of complete and partial hydatidiform mole, and the …

Gestational trophoblastic disease II: classification and management of gestational trophoblastic neoplasia

JR Lurain - American journal of obstetrics and gynecology, 2011 - Elsevier
Gestational trophoblastic neoplasia (GTN) includes invasive mole, choriocarcinoma,
placental site trophoblastic tumor, and epithelioid trophoblastic tumor. The overall cure rate …

Pembrolizumab is effective for drug-resistant gestational trophoblastic neoplasia

E Ghorani, B Kaur, RA Fisher, D Short, U Joneborg… - The Lancet, 2017 - thelancet.com
Gestational trophoblastic disease represents a spectrum of pregnancy related disorders,
ranging from pre-malignant hydatidiform mole to malignant tumours, collectively referred to …

Camrelizumab plus apatinib in patients with high-risk chemorefractory or relapsed gestational trophoblastic neoplasia (CAP 01): a single-arm, open-label, phase 2 …

H Cheng, L Zong, Y Kong, X Wang, Y Gu… - The Lancet …, 2021 - thelancet.com
Background Treatment options for patients with high-risk chemorefractory or relapsed
gestational trophoblastic neoplasia are scarce. The synergistic antitumour effect of …

Gestational trophoblastic neoplasia, version 2.2019, NCCN clinical practice guidelines in oncology

NR Abu-Rustum, CM Yashar, S Bean, K Bradley… - Journal of the National …, 2019 - jnccn.org
Gestational trophoblastic neoplasia (GTN), a subset of gestational trophoblastic disease
(GTD), occurs when tumors develop in the cells that would normally form the placenta during …

Avelumab in patients with gestational trophoblastic tumors with resistance to single-agent chemotherapy: cohort A of the TROPHIMMUN phase II trial

B You, PA Bolze, JP Lotz, J Massardier… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE Women with gestational trophoblastic tumors (GTT) resistant to single-agent
chemotherapy receive alternative chemotherapy regimens, which, although effective, cause …

Current management of gestational trophoblastic neoplasia

DP Goldstein, RS Berkowitz - Hematology/Oncology Clinics, 2012 - hemonc.theclinics.com
Gestational trophoblastic neoplasms (GTN) are malignant lesions that arise from placental
villous and extravillous trophoblast. Four clinicopathologic conditions make up this entity:(1) …

Treatment of gestational trophoblastic disease in the 2020s

JJ Clark, S Slater, MJ Seckl - Current opinion in obstetrics and …, 2021 - journals.lww.com
Checkpoint inhibitors are likely to play an increasing role in the future management of GTN
management. Further refinement of prognostic factors to identify those most at risk of GTN …

Gestational trophoblastic tumours: an update for 2014

FEM Froeling, MJ Seckl - Current oncology reports, 2014 - Springer
Gestational trophoblastic disease describes a variety of pregnancy-related diseases
including the premalignant conditions of a partial and complete hydatidiform mole and the …

[HTML][HTML] Advances in the diagnosis and early management of gestational trophoblastic disease

CM Joyce, B Fitzgerald, TV McCarthy, J Coulter… - BMJ …, 2022 - ncbi.nlm.nih.gov
Gestational trophoblastic disease describes a group of rare pregnancy related disorders that
span a spectrum of premalignant and malignant conditions. Hydatidiform mole (also termed …