As a carrier of many biologically active compounds, blood is exposed to oxidants to a
greater extent than the intracellular environment. Serum albumin plays a key role in …

Excessive fat accumulation in the liver has become a major health threat worldwide.
Unresolved fat deposition in the liver can go undetected until it develops into fatty liver …

Hyperuricemia is a metabolic disease caused by purine nucleotide metabolism disorder.
The prevalence of hyperuricemia is increasing worldwide, with a growing trend in the …

Objective Accumulating evidence indicates that high uric acid (UA) is strongly associated
with obesity and metabolic syndrome and drives the development of nonalcoholic fatty liver …

Changes in lifestyle induce an increase in patients with hyperuricemia (HUA), leading to
gout, gouty arthritis, renal damage, and cardiovascular injury. There is a strong inflammatory …

Background An elevated level of plasma uric acid has been widely recognized as a risk
factor for non-alcoholic fatty liver disease (NAFLD), where oxidative stress and inflammation …

Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in the
world. Sustained hepatic inflammation is a key driver of the transition from simple fatty liver …

Xanthine oxidoreductase (XOR) is an enzyme found in various organisms. It converts
hypoxanthine to xanthine and urate, which are crucial steps in purine elimination in humans …

In recent years, metabolic syndrome (Mets) has been a hot topic among medical scientists.
Mets has an intimate relationship with the incidence and development of various cancers. As …

Hyperglycemia and hyperuricemia are both metabolic disorders related to excessive amount
of metabolites in blood, which are considered as high risk factors for the development of …