Molecular beacons

W Tan, K Wang, TJ Drake - Current opinion in chemical biology, 2004 - Elsevier
This opinion covers the field of molecular beacons (MBs), in which nucleic acids are
molecularly engineered to have unique functions for the investigation of biomolecules …

Peptide synthesis: chemical or enzymatic

F Guzmán, S Barberis, A Illanes - Electronic Journal of Biotechnology, 2007 - SciELO Chile
Peptides are molecules of paramount importance in the fields of health care and nutrition.
Several technologies for their production are now available, among which chemical and …

Immunological and molecular diagnosis of cysticercosis

S Rodriguez, P Wilkins, P Dorny - Pathogens and global health, 2012 - Taylor & Francis
Cysticercosis, the infection with the larval stage of Taenia solium, is a cause of neurological
symptoms including seizures, affecting the quality of life of patients and their families …

EpitopeVec: linear epitope prediction using deep protein sequence embeddings

A Bahai, E Asgari, MRK Mofrad, A Kloetgen… - …, 2021 - academic.oup.com
Motivation B-cell epitopes (BCEs) play a pivotal role in the development of peptide vaccines,
immuno-diagnostic reagents and antibody production, and thus in infectious disease …

Synthetic peptides for the immunodiagnosis of human diseases

MJ Gomara, I Haro - Current medicinal chemistry, 2007 - ingentaconnect.com
Synthetic peptides have been shown to be valuable tools for viral laboratory diagnosis and
can provide uniform, chemically well-defined antigens for antibody analysis, reducing inter …

Proteins selected in Leishmania (Viannia) braziliensis by an immunoproteomic approach with potential serodiagnosis applications for tegumentary leishmaniasis

MC Duarte, DC Pimenta… - Clinical and Vaccine …, 2015 - Am Soc Microbiol
The serodiagnosis of human tegumentary leishmaniasis (TL) presents some problems, such
as the low level of antileishmanial antibodies found in most of the patients, as well as the …

[PDF][PDF] B cell epitope prediction

JV Ponomarenko… - Structural …, 2009 - researchgate.net
When a living organism encounters a pathogenic virus or microbe, the B cells of the immune
system recognize the pathogen's antigens by their membrane-bound immunoglobulin …

Next-generation ELISA diagnostic assay for Chagas Disease based on the combination of short peptidic epitopes

J Mucci, SJ Carmona, R Volcovich… - PLoS neglected …, 2017 - journals.plos.org
Chagas Disease, caused by the protozoan Trypanosoma cruzi, is a major health and
economic problem in Latin America for which no vaccine or appropriate drugs for large …

Serodiagnosis of Echinococcus spp. Infection: Explorative Selection of Diagnostic Antigens by Peptide Microarray

C List, W Qi, E Maag, B Gottstein… - PLoS neglected …, 2010 - journals.plos.org
Background Production of native antigens for serodiagnosis of helminthic infections is
laborious and hampered by batch-to-batch variation. For serodiagnosis of echinococcosis …

[HTML][HTML] A systematic review of peptide-based serological tests for the diagnosis of leishmaniasis

J Pagniez, E Petitdidier, O Parra-Zuleta, J Pissarra… - Parasite, 2023 - ncbi.nlm.nih.gov
Serological methods should meet the needs of leishmaniasis diagnosis due to their high
sensitivity and specificity, economical and adaptable rapid diagnostic test format, and ease …