The pyran ring system is widely present in the animal and plant kingdom and possesses
diverse pharmacological activities. Pyran is a six-membered oxygen heterocycle with two …

Abstract 2H-Pyran-2-ones are widely present in nature and found as either isolated or in
fused form. Depending on the fusion of benzene ring, pyran can give coumarins …

Progress in Heterocyclic Chemistry (PHC) is an annual review series commissioned by the
International Society of Heterocyclic Chemistry (ISHC). Volumes in the series contain both …

A general route to α-pyrones and 3-substituted isocoumarins from (Z)-iodovinylic acids 1a− f
or 2-iodobenzoic acids 4a− c is described, including compounds bearing a substituent on …

Stereoselective synthesis of novel annulated thiopyrano indole derivatives from simple oxindole
via intramolecular 1,3-dipolar cycloaddition reactions of nitrone and nitrile oxide - ScienceDirect …

A new and metal-free approach to the synthesis of substituted 6H-benzo [c] chromenes has
been developed. This three-step synthetic sequence starts from variously substituted …

Protein tyrosine phosphatase 1B (PTP1B) is an enzyme that plays a critical role in down-
regulating insulin signaling through dephosphorylation of the insulin receptor. Inhibitors of …

The aim of this paper is to present the synthesis and reactions of thiochroman-4-ones. These
compounds are used as precursors for the synthesis of many heterocyclic rings. The …

A highly efficient domino protocol has been developed for the synthesis of 6-aryl-4-
(methylthio/amine-1-yl)-2-oxo-2 H-pyran-3-carbonitriles and 4-aryl-2-(amine-1-yl)-5, 6, 7, 8 …

Abstract The 6‐substituted 3‐bromo‐5‐iodo‐2 (2H)‐pyranones 11, prepared by
iodolactonization of the corresponding 5‐substituted (E)‐2‐bromo‐2‐en‐4‐ynoic acids 10 …