Soon after they were first described in 1990, aptamers were largely recognized as a new
class of biological ligands that can rival antibodies in various analytical, diagnostic, and …

Nucleic acids are gaining significant attention as versatile building blocks for the next
generation of soft materials. Due to significant advances in the chemical synthesis and …

Aptamers are single-stranded nucleic acid molecules that bind to and inhibit proteins and
are commonly produced by systematic evolution of ligands by exponential enrichment …

Nucleolin or C23, is one of the most abundant non-ribosomal phosphoproteins of nucleolus.
However, in several cancers, nucleolin is highly expressed both intracellularly and on the …

Using nanoparticles to carry and delivery anticancer drugs holds much promise in cancer
therapy, but nanoparticles per se are lacking specificity. Active targeting, that is, using …

Lipid-based polymeric nanoparticles are the highly popular carrier systems for cancer drug
therapy. But presently, detailed investigations have revealed their flaws as drug delivery …

Breast cancer is the most prevalent cancer among women worldwide. However, increased
survival is due to the dramatic advances in the screening methods, early diagnosis, and …

The recent emergence of nanomedicine has revolutionized the therapeutic landscape and
necessitated the creation of more sophisticated drug delivery systems. Polymeric …

Aptamers are a class of small nucleic acid ligands that are composed of RNA or single-
stranded DNA oligonucleotides and have high specificity and affinity for their targets. Similar …

Aptamers are short single-stranded oligonucleotides that are capable of binding various
molecules with high affinity and specificity. When the technology of aptamer selection was …