Wound healing: cellular mechanisms and pathological outcomes

HN Wilkinson, MJ Hardman - Open biology, 2020 - royalsocietypublishing.org
Wound healing is a complex, dynamic process supported by a myriad of cellular events that
must be tightly coordinated to efficiently repair damaged tissue. Derangement in wound …

Biomimetic hydrogels to promote wound healing

F Fan, S Saha, D Hanjaya-Putra - Frontiers in Bioengineering and …, 2021 - frontiersin.org
Wound healing is a common physiological process which consists of a sequence of
molecular and cellular events that occur following the onset of a tissue lesion in order to …

A flexible multiplexed immunosensor for point-of-care in situ wound monitoring

Y Gao, DT Nguyen, T Yeo, SB Lim, WX Tan… - Science …, 2021 - science.org
Chronic wounds arise from interruption of normal healing due to many potential
pathophysiological factors. Monitoring these multivariate factors can provide personalized …

Electrospun nanofibers promote wound healing: Theories, techniques, and perspectives

C Gao, L Zhang, J Wang, M Jin, Q Tang… - Journal of Materials …, 2021 - pubs.rsc.org
At present, the clinical strategies for treating chronic wounds are limited, especially when it
comes to pain relief and rapid wound healing. Therefore, there is an urgent need to develop …

Re-epithelialization of adult skin wounds: Cellular mechanisms and therapeutic strategies

P Rousselle, F Braye, G Dayan - Advanced Drug Delivery Reviews, 2019 - Elsevier
Cutaneous wound healing in adult mammals is a complex multi-step process involving
overlapping stages of blood clot formation, inflammation, re-epithelialization, granulation …

Silver nanoparticle impregnated chitosan-PEG hydrogel enhances wound healing in diabetes induced rabbits

N Masood, R Ahmed, M Tariq, Z Ahmed… - International journal of …, 2019 - Elsevier
Non-healing wounds are among the serious complications of type-2-diabetes around the
globe, associated with high incidence of bacterial infection, chronic nerve and blood vessel …

Nitric oxide therapy for diabetic wound healing

MJ Malone‐Povolny, SE Maloney… - Advanced healthcare …, 2019 - Wiley Online Library
Nitric oxide (NO) represents a potential wound therapeutic agent due to its ability to regulate
inflammation and eradicate bacterial infections. Two broad strategies exist to utilize NO for …

Chronic diabetic wounds and their treatment with skin substitutes

J Holl, C Kowalewski, Z Zimek, P Fiedor, A Kaminski… - Cells, 2021 - mdpi.com
With the global prevalence of type 2 diabetes mellitus steeply rising, instances of chronic,
hard-healing, or non-healing diabetic wounds and ulcers are predicted to increase. The …

Implementing TIMERS: the race against hard-to-heal wounds

L Atkin, Z Bućko, EC Montero, K Cutting… - Journal of wound …, 2019 - magonlinelibrary.com
There may be significant deficiencies in the knowledge among nurses, 38–40 an issue
recognised by many. 41 A survey of community nurses in Ireland found that more than half …

Cellular and molecular mechanisms of repair in acute and chronic wound healing

P Martin, R Nunan - British Journal of Dermatology, 2015 - academic.oup.com
A considerable understanding of the fundamental cellular and molecular mechanisms
underpinning healthy acute wound healing has been gleaned from studying various animal …