Mesenchymal stem/stromal cell-based therapy: mechanism, systemic safety and biodistribution for precision clinical applications
WZ Zhuang, YH Lin, LJ Su, MS Wu, HY Jeng… - Journal of biomedical …, 2021 - Springer
Mesenchymal stem/stromal cells (MSCs) are a promising resource for cell-based therapy
because of their high immunomodulation ability, tropism towards inflamed and injured …
because of their high immunomodulation ability, tropism towards inflamed and injured …
Advances in mesenchymal stem cell conditioned medium-mediated periodontal tissue regeneration
H Lin, H Chen, X Zhao, Z Chen, P Zhang, Y Tian… - Journal of translational …, 2021 - Springer
Periodontitis is a chronic inflammatory disease that leads to the destruction of both soft and
hard periodontal tissues. Complete periodontal regeneration in clinics using the currently …
hard periodontal tissues. Complete periodontal regeneration in clinics using the currently …
Comparative analysis of magnetically activated cell sorting and ultracentrifugation methods for exosome isolation
Mesenchymal stem cell-derived exosomes regulate cell migration, proliferation,
differentiation, and synthesis of the extracellular matrix, giving great potential for the …
differentiation, and synthesis of the extracellular matrix, giving great potential for the …
The immunomodulatory role of cell-free approaches in SARS-coV-2-induced cytokine storm—A powerful therapeutic tool for COVID-19 patients
M Csobonyeiova, V Smolinska, S Harsanyi… - Biomedicines, 2023 - mdpi.com
Currently, there is still no effective and definitive cure for the coronavirus disease 2019
(COVID-19) caused by the infection of the novel highly contagious severe acute respiratory …
(COVID-19) caused by the infection of the novel highly contagious severe acute respiratory …
SA/G hydrogel containing hCAP-18/LL-37-engineered WJ-MSCs-derived conditioned medium promoted wound healing in rat model of excision injury
Aim Development and design of efficient wound dressings are subject of intensive
investigations either in basic or in clinical researches. Although, hydrogel-based wound …
investigations either in basic or in clinical researches. Although, hydrogel-based wound …
Hypoxic extracellular matrix preserves its competence after expansion of human MSCs under physiological hypoxia in vitro
D Matveeva, S Buravkov, E Andreeva, L Buravkova - Biomimetics, 2023 - mdpi.com
Tissue-relevant O2 levels are considered as an important tool for the preconditioning of
multipotent mesenchymal stromal cells (MSCs) for regenerative medicine needs. The …
multipotent mesenchymal stromal cells (MSCs) for regenerative medicine needs. The …
Therapeutic role of exosomes and conditioned medium in keloid and hypertrophic scar and possible mechanisms
Y Zhong, Y Zhang, A Yu, Z Zhang, Z Deng… - Frontiers in …, 2023 - frontiersin.org
Exosomes, ranging from 40 to 160 nm in diameter, are extracellular lipid bilayer
microvesicles that regulate the body's physiological and pathological processes and are …
microvesicles that regulate the body's physiological and pathological processes and are …
The effects of Wharton's jelly MSCs secretomes for restoring busulfan-induced reproductive toxicity in male mice
S Bahmyari, S Alaee, Z Khodabandeh… - Human & …, 2024 - journals.sagepub.com
Several studies investigated the application of Mesenchymal stem cells (MSCs) for treating
spermatogenic disorders. Considering the limitation of MSC application, the present study …
spermatogenic disorders. Considering the limitation of MSC application, the present study …
Mesenchymal stem cell-derived exosomes for managing graft-versus-host disease: An updated view
Graft-versus-host disease (GvHD) is the most common complication after stem cell
transplantation, and also it is one of the primary limiting factors for the use of hematopoietic …
transplantation, and also it is one of the primary limiting factors for the use of hematopoietic …
Mesenchymal-stem cell-derived conditioned media versus exosomes in the treatment of rat model of polycystic ovary: an attempt to understand the underlying …
SAE Abd-Elwahab, NH Khamis… - Microscopy and …, 2023 - academic.oup.com
Polycystic ovary syndrome (PCOS) is one of the most common endocrine and reproductive
disorders throughout female reproductive age. Cell free therapy [conditioned media (CM) & …
disorders throughout female reproductive age. Cell free therapy [conditioned media (CM) & …