Pathogenesis of HIV-related lung disease: immunity, infection, and inflammation
SK Cribbs, K Crothers, A Morris - Physiological reviews, 2020 - journals.physiology.org
Despite anti-retroviral therapy (ART), human immunodeficiency virus-1 (HIV)-related
pulmonary disease continues to be a major cause of morbidity and mortality for people living …
pulmonary disease continues to be a major cause of morbidity and mortality for people living …
Adverse events in people taking macrolide antibiotics versus placebo for any indication
Background Macrolide antibiotics (macrolides) are among the most commonly prescribed
antibiotics worldwide and are used for a wide range of infections. However, macrolides also …
antibiotics worldwide and are used for a wide range of infections. However, macrolides also …
Composition of gut microbiota of children and adolescents with perinatal human immunodeficiency virus infection taking antiretroviral therapy in Zimbabwe
TT Flygel, E Sovershaeva… - The Journal of …, 2020 - academic.oup.com
Background Human immunodeficiency virus (HIV) infection causes impairment of the
gastrointestinal barrier, with substantial depletion of CD4+ T cells in the gut. Antiretroviral …
gastrointestinal barrier, with substantial depletion of CD4+ T cells in the gut. Antiretroviral …
Effect of once-weekly azithromycin vs placebo in children with HIV-associated chronic lung disease: the BREATHE randomized clinical trial
RA Ferrand, G McHugh, AM Rehman… - JAMA Network …, 2020 - jamanetwork.com
Importance HIV-associated chronic lung disease (HCLD) in children is associated with small
airways disease, is common despite antiretroviral therapy (ART), and is associated with …
airways disease, is common despite antiretroviral therapy (ART), and is associated with …
Update: Vitamin D3 and calcium carbonate supplementation for adolescents with HIV to reduce musculoskeletal morbidity and immunopathology (VITALITY trial) …
NV Dzavakwa, M Chisenga, G McHugh, S Filteau… - Trials, 2024 - Springer
Background Of the 2 million children living with HIV globally, 90% live in sub-Saharan Africa.
Despite antiretroviral therapy, longstanding HIV infection is associated with several chronic …
Despite antiretroviral therapy, longstanding HIV infection is associated with several chronic …
Growth Profiles of Children and Adolescents Living with and without Perinatal HIV Infection in Southern Africa: A Secondary Analysis of Cohort Data
Impaired linear growth and slower pubertal growth can be associated with perinatal HIV
infection. We characterised growth relative to population norms, among the full adolescent …
infection. We characterised growth relative to population norms, among the full adolescent …
Adherence to additional medication for management of HIV-associated comorbidities among older children and adolescents taking antiretroviral therapy
Background Management of co-morbidities among persons living with HIV is an emerging
priority, which may require additional medication over and above life-long antiretroviral …
priority, which may require additional medication over and above life-long antiretroviral …
Risk factors for sustained virological non-suppression among children and adolescents living with HIV in Zimbabwe and Malawi: a secondary data analysis
C Jackson, AM Rehman, G McHugh… - BMC pediatrics, 2022 - Springer
Background We investigated risk factors for sustained virological non-suppression (viral
load≥ 1000 copies/ml on two tests 48 weeks apart) among children and adolescents …
load≥ 1000 copies/ml on two tests 48 weeks apart) among children and adolescents …
Guardians and research staff experiences and views about the consent process in hospital-based paediatric research studies in urban Malawi: A qualitative study
MJ Gondwe, NM Toto, C Gunda, M Gmeiner… - BMC medical …, 2022 - Springer
Background Obtaining consent has become a standard way of respecting the patient's rights
and autonomy in clinical research. Ethical guidelines recommend that the child's parent/s or …
and autonomy in clinical research. Ethical guidelines recommend that the child's parent/s or …
Chronic lung disease in children and adolescents with HIV: a case–control study
Objective To describe the features of HIV‐associated chronic lung disease (CLD) in older
children and adolescents living with HIV and to examine the clinical factors associated with …
children and adolescents living with HIV and to examine the clinical factors associated with …