Fusobacterium nucleatum — symbiont, opportunist and oncobacterium

CA Brennan, WS Garrett - Nature Reviews Microbiology, 2019 - nature.com
Fusobacterium nucleatum has long been found to cause opportunistic infections and has
recently been implicated in colorectal cancer; however, it is a common member of the oral …

Modulating the microbiome to improve therapeutic response in cancer

JL McQuade, CR Daniel, BA Helmink… - The Lancet …, 2019 - thelancet.com
Although novel therapies, including immunotherapy, have dramatically improved outcomes
for many patients with cancer, overall outcomes are heterogeneous and existing biomarkers …

Microbiome Dependent Regulation of Tregs and Th17 Cells in Mucosa

P Pandiyan, N Bhaskaran, M Zou, E Schneider… - Frontiers in …, 2019 - frontiersin.org
Mammals co-exist with resident microbial ecosystem that is composed of an incredible
number and diversity of bacteria, viruses and fungi. Owing to direct contact between resident …

Immune system, microbiota, and microbial metabolites: the unresolved triad in colorectal cancer microenvironment

M Hanus, D Parada-Venegas, G Landskron… - Frontiers in …, 2021 - frontiersin.org
Colorectal cancer (CRC) is one of the most common cancers worldwide. As with other
cancers, CRC is a multifactorial disease due to the combined effect of genetic and …

Role of the oral microbiota in cancer evolution and progression

J Sun, Q Tang, S Yu, M Xie, Y Xie, G Chen… - Cancer …, 2020 - Wiley Online Library
Bacteria identified in the oral cavity are highly complicated. They include approximately
1000 species with a diverse variety of commensal microbes that play crucial roles in the …

[HTML][HTML] Tumorigenic bacteria in colorectal cancer: mechanisms and treatments

S Li, J Liu, X Zheng, L Ren, Y Yang, W Li… - Cancer biology & …, 2022 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is the third most common and the second most fatal cancer. In
recent years, more attention has been directed toward the role of gut microbiota in the …

Colon carcinogenesis: the interplay between diet and gut microbiota

YL Loke, MT Chew, YF Ngeow, WWD Lim… - Frontiers in cellular and …, 2020 - frontiersin.org
Colorectal cancer (CRC) incidence increases yearly, and is three to four times higher in
developed countries compared to developing countries. The well-known risk factors have …

Fusobacterium nucleatum Acts as a Pro-carcinogenic Bacterium in Colorectal Cancer: From Association to Causality

S Wang, Y Liu, J Li, L Zhao, W Yan, B Lin… - Frontiers in Cell and …, 2021 - frontiersin.org
Colorectal cancer (CRC) is a common cancer worldwide with complex etiology.
Fusobacterium nucleatum (F. nucleatum), an oral symbiotic bacterium, has been linked with …

Fusobacterium nucleatum is associated with worse prognosis in Lauren's diffuse type gastric cancer patients

ET Boehm, C Thon, J Kupcinskas, R Steponaitiene… - Scientific reports, 2020 - nature.com
Fusobacterium nucleatum (F. nucleatum) is frequently detected in primary colorectal cancer
(CRC) and matching metastasis, and has been linked to a worse prognosis. We investigated …

Gut dysbiosis and intestinal barrier dysfunction: potential explanation for early-onset colorectal cancer

SM Ahmad Kendong, RA Raja Ali… - Frontiers in cellular …, 2021 - frontiersin.org
Colorectal cancer (CRC) is a heterogeneous disease that commonly affects individuals
aged more than 50 years old globally. Regular colorectal screening, which is recommended …