Design and applications of water-soluble coordination cages

EG Percástegui, TK Ronson, JR Nitschke - Chemical Reviews, 2020 - ACS Publications
Compartmentalization of the aqueous space within a cell is necessary for life. In similar
fashion to the nanometer-scale compartments in living systems, synthetic water-soluble …

DNA functional materials assembled from branched DNA: design, synthesis, and applications

Y Dong, C Yao, Y Zhu, L Yang, D Luo… - Chemical Reviews, 2020 - ACS Publications
DNA is traditionally known as a central genetic biomolecule in living systems. From an
alternative perspective, DNA is a versatile molecular building-block for the construction of …

Molecular methods for assessment of non-covalent metallodrug–DNA interactions

A Kellett, Z Molphy, C Slator, V McKee… - Chemical Society …, 2019 - pubs.rsc.org
The binding of small molecule metallodrugs to discrete regions of nucleic acids is an
important branch of medicinal chemistry and the nature of these interactions, allied with …

Supramolecular coordination: self-assembly of finite two-and three-dimensional ensembles

R Chakrabarty, PS Mukherjee, PJ Stang - Chemical reviews, 2011 - ACS Publications
Fascination with supramolecular chemistry over the past few decades has led to the
synthesis of an ever-increasing number of elegant and intricate functional structures with …

Anticancer activity of complexes of the third row transition metals, rhenium, osmium, and iridium

CC Konkankit, SC Marker, KM Knopf, JJ Wilson - Dalton Transactions, 2018 - pubs.rsc.org
The clinical success of the platinum-based chemotherapeutic agents has prompted the
investigation of coordination and organometallic complexes of alternative metal centers for …

Metal complex interactions with DNA

BJ Pages, DL Ang, EP Wright, JR Aldrich-Wright - Dalton transactions, 2015 - pubs.rsc.org
Increasing numbers of DNA structures are being revealed using biophysical, spectroscopic
and genomic methods. The diversity of transition metal complexes is also growing, as the …

Ruthenium (II) polypyridyl complexes and DNA—from structural probes to cellular imaging and therapeutics

MR Gill, JA Thomas - Chemical Society Reviews, 2012 - pubs.rsc.org
In the last few decades, coordination complexes based on d6 metal centres and polypyridyl
ligand architectures been developed as structure-and site-specific reversible DNA binding …

Biomedical and biochemical applications of self-assembled metallacycles and metallacages

TR Cook, V Vajpayee, MH Lee, PJ Stang… - Accounts of chemical …, 2013 - ACS Publications
Metal ions and metal complexes with organic molecules are ubiquitous in nature. Bulk metal
ions of Na, K, Mg, and Ca constitute as much as 1% of human body weight. The remaining …

New trends for metal complexes with anticancer activity

PCA Bruijnincx, PJ Sadler - Current opinion in chemical biology, 2008 - Elsevier
Medicinal inorganic chemistry can exploit the unique properties of metal ions for the design
of new drugs. This has, for instance, led to the clinical application of chemotherapeutic …

The promise of self-assembled 3D supramolecular coordination complexes for biomedical applications

A Casini, B Woods, M Wenzel - Inorganic Chemistry, 2017 - ACS Publications
In the supramolecular chemistry field, coordination-driven self-assembly has provided the
basis for tremendous growth across many subdisciplines, spanning from fundamental …