Increasing evidence sustains that the establishment and maintenance of many, if not all,
human cancers are due to cancer stem cells (CSCs), tumor cells with stem cell properties …

Micro RNA s are a class of small non‐coding RNA s involved in the transcriptional and post‐
transcriptional regulation of gene expression. The function of mi RNA s in liver disease …

Cbx4 is a polycomb group protein that is also a SUMO E3 ligase, but its potential roles in
tumorigenesis remain to be explored. Here, we report that Cbx4, but not other members of …

Background Hepatocellular carcinoma (HCC) is one of the most common malignancies with
a high morbidity and mortality worldwide. MicroRNAs are key regulators of HCC genesis …

Background Hepatocellular carcinoma (HCC) is the sixth most common cancer in the world.
Having a very poor prognosis, it currently ranks as the third most common cause of cancer …

Abstract c-Met receptor tyrosine kinase has been regarded as a promising therapeutic target
for hepatocellular carcinoma (HCC). Recently, microRNAs (miRNAs) have been shown as a …

Hepatocellular carcinoma (HCC), the most common primary tumor of the liver, has a poor
prognosis and rapid progression. MicroRNAs (miRNAs) play important roles in …

Hepatocellular carcinoma (HCC) is one of the most common and rapidly fatal malignancies
worldwide with a multifactorial, multistep, complex process and poor prognosis. Its early …

In Egypt, liver diseases are exceptionally high, maintaining the highest prevalence of
hepatitis C virus (HCV) worldwide, and increasing rates of hepatocellular carcinoma (HCC) …

Human hepatoma (HCC) has been reported to be strongly resistant to Fas-mediated
apoptosis. However, the underlying mechanisms are poorly understood. In this study the …