Pharmaceutical cocrystals are multicomponent systems in which at least one component is
an active pharmaceutical ingredient and the others are pharmaceutically acceptable …

Mechanical behavior of pharmaceutical crystals directly impacts the formulation
development and manufacturing of drug products. The understanding of crystal structure …

The mechanical properties of crystalline materials are crucial knowledge for their screening,
design, and exploitation. Density functional theory (DFT), remains one of the most effective …

Stimuli-responsive crystals have aroused tremendous interest due to their potential as smart
materials. However, endowing mono-component crystals with multiple stimuli-responsive …

Two polymorphic cocrystals of palmatine chloride with racemic hesperetin (Form I and Form
II) have been prepared and investigated systematically. Crystal structure analysis reveals …

The distinct mechanical properties of concomitant dimorphs (Form α and Form β) of 1, 3-bis
(4-nitrophenyl) thiourea–DMSO solvate (TU-DMSO) have been investigated via …

Paritaprevir and ombitasvir are part of a triple combination, first-generation, direct-acting
antiviral regimen as a fixed-dose tablet. The commercially manufactured Form II of …

A structure–property analysis of ten compositionally and chemically similar co-crystals of N-
(pyridin-2-yl) alkylamides and carboxylic acids shows that three co-crystals of targets …

Flexible organic crystals are emerging as a potential candidate for smart materials and have
aroused great interest over the past decade. In view of multicomponent supramolecular …

A long alkyl-chained organic molecule, 4, 5, 6, 7-tetrachloro-2-dodecylisoindoline-1, 3-dione
(1), was crystallized into needle-like crystals in dichloromethane (1DCM) or plate-like ones …