Adiponectin is one of the most important adipocytokines secreted by adipocytes and is
called a “guardian angel adipocytokine” owing to its unique biological functions. Adiponectin …

Adiponectin, first described in the mid-1990s, is one of the most widely studied adipokines to
date. Studies of its regulation, biogenesis and physiological effects have yielded great …

Adipose tissue is now recognized as an important endocrine organ, capable of secreting a
large number of endocrine factors which regulate a wide variety of physiological functions …

Over the past two decades our view of adipose tissue has undergone a dramatic change
from an inert energy storage tissue to an active endocrine organ. Adipose tissue …

Adiponectin is a fat-derived hormone whose reduction plays central roles in obesity-linked
diseases including insulin resistance/type 2 diabetes and atherosclerosis. The cloning of …

Chronic inflammation and reduced adiponectin are widely observed in the white adipose
tissue in obesity. However, the cause of the changes remains to be identified. In this study …

As sensors for fat-soluble hormones and dietary lipids, oscillations in nuclear receptor (NR)
expression in key metabolic tissues may contribute to circadian entrainment of nutrient and …

Recent studies consistently support a hypoxia response in the adipose tissue in obese
animals. The observations have led to the formation of an exciting concept, adipose tissue …

Iron overload is associated with increased diabetes risk. We therefore investigated the effect
of iron on adiponectin, an insulin-sensitizing adipokine that is decreased in diabetic patients …

Menopause is associated with increased adiposity and greater risk of metabolic disease. In
the ovariectomized (OVX) rodent model of menopause, increased adiposity is prevented by …