[HTML][HTML] Cytokines in atherosclerosis: Key players in all stages of disease and promising therapeutic targets

DP Ramji, TS Davies - Cytokine & growth factor reviews, 2015 - Elsevier
Atherosclerosis, a chronic inflammatory disorder of the arteries, is responsible for most
deaths in westernized societies with numbers increasing at a marked rate in developing …

The IL-20 subfamily of cytokines—from host defence to tissue homeostasis

S Rutz, X Wang, W Ouyang - Nature Reviews Immunology, 2014 - nature.com
Abstract The interleukin-20 (IL-20) subfamily of cytokines comprises IL-19, IL-20, IL-22, IL-24
and IL-26. These cytokines are all members of the larger IL-10 family, but have been …

The arterial microenvironment: the where and why of atherosclerosis

A Yurdagul Jr, AC Finney, MD Woolard… - Biochemical …, 2016 - portlandpress.com
The formation of atherosclerotic plaques in the large and medium sized arteries is classically
driven by systemic factors, such as elevated cholesterol and blood pressure. However, work …

Adaptive (T and B cells) immunity and control by dendritic cells in atherosclerosis

H Ait-Oufella, AP Sage, Z Mallat, A Tedgui - Circulation research, 2014 - Am Heart Assoc
Chronic inflammation in response to lipoprotein accumulation in the arterial wall is central in
the development of atherosclerosis. Both innate and adaptive immunity are involved in this …

Atherosclerosis: orchestrating cells and biomolecules involved in its activation and inhibition

A Munjal, R Khandia - Advances in protein chemistry and structural biology, 2020 - Elsevier
The term atherosclerosis refers to the condition of deposition of lipids and other substances
in and on the artery walls, called as plaque that restricts the normal blood flow. The plaque …

DPP4 inhibition impairs senohemostasis to improve plaque stability in atherosclerotic mice

AB Herman, D Tsitsipatis, C Anerillas… - The Journal of …, 2023 - Am Soc Clin Investig
Senescent vascular smooth muscle cells (VSMCs) accumulate in the vasculature with age
and tissue damage and secrete factors that promote atherosclerotic plaque vulnerability and …

Challenging the paradigm: anti-inflammatory interleukins and angiogenesis

AM Peluzzo, MV Autieri - Cells, 2022 - mdpi.com
Angiogenesis is a vital biological process, and neovascularization is essential for the
development, wound repair, and perfusion of ischemic tissue. Neovascularization and …

Modulation of immune‐inflammatory responses in abdominal aortic aneurysm: Emerging molecular targets

H Li, S Bai, Q Ao, X Wang, X Tian, X Li… - Journal of …, 2018 - Wiley Online Library
Abdominal aortic aneurysm (AAA), a deadly vascular disease in human, is a chronic
degenerative process of the abdominal aorta. In this process, inflammatory responses and …

Cytokines and their role in cardiovascular diseases

H Haybar, B Bandar, E Torfi, A Mohebbi, N Saki - Cytokine, 2023 - Elsevier
The evaluation of diagnostic and prognostic biomarkers has always been a hot topic in
various diseases. Considering that cardiovascular diseases (CVDs) have the highest …

The role of interleukin-10 family members in cardiovascular diseases

S Xu, J Zhang, J Liu, J Ye, Y Xu, Z Wang, J Yu… - International …, 2021 - Elsevier
Abstract Interleukin (IL)-10 cytokine family members, including IL-10, IL-19, IL-20, IL-22, IL-
24, IL-26 and the distantly related IL-28A, IL-28B, and IL-29, play critical roles in the …