Chemokines and cytokines are critical for initiating and coordinating the organized and
sequential recruitment and activation of cells into Mycobacterium tuberculosis-infected …

The majority of the 30–100 million people infected with Strongyloides stercoralis, a soil
transmitted intestinal nematode, have subclinical (or asymptomatic) infections. These …

Activation of cells in the adaptive immune system is a highly orchestrated process dictated
by multiples cues from the innate immune system. Although the fundamental principles of …

Mycobacterium tuberculosis (M. tb), the causative agent of tuberculosis (TB), is the current
leading cause of death due to a single infectious organism. Although curable, the broad …

Parasites have evolved a wide range of mechanisms that they use to evade or manipulate
the host's immune response and establish infection. The majority of the in vivo studies that …

A characteristic feature of host responses to helminth infections is the development of
profound systemic and tissue-localised Type 2 immune responses that play critical roles in …

Over 2 billion people worldwide are infected with helminths (worms). Similarly, infection with
Mycobacterium tuberculosis (Mtb) occurs in over a third of the world's population, often with …

Background Dynamic interactions between the host and gastrointestinal microbiota play an
important role for local and systemic immune homeostasis. Helminthic parasites modulate …

Background: Persons with HIV (PWH) on antiretroviral therapy (ART) have persistent
immune activation associated with increased risk for non-AIDS related diseases. Latent …

In many settings, adults with active or latent tuberculosis will also be coinfected with
helminths. Our study aimed to investigate how anthelmintic treatment modulates …