The importance of antimicrobial resistance in medical mycology
Prior to the SARS-CoV-2 pandemic, antibiotic resistance was listed as the major global
health care priority. Some analyses, including the O'Neill report, have predicted that deaths …
health care priority. Some analyses, including the O'Neill report, have predicted that deaths …
Emerging Fungal Infections: from the Fields to the Clinic, Resistant Aspergillus fumigatus and Dermatophyte Species: a One Health Perspective on an Urgent Public …
A Langfeldt, JAW Gold, T Chiller - Current Clinical Microbiology Reports, 2022 - Springer
Abstract Purpose of Review For this review, we use a One Health approach to examine two
globally emerging public health threats related to antifungal drug resistance: triazole …
globally emerging public health threats related to antifungal drug resistance: triazole …
[PDF][PDF] Amphotericin B: A comprehensive overview of its clinical applications and toxicity management
I Karunarathna, U Ekanayake, K Gunawardana… - 2024 - researchgate.net
Amphotericin B deoxycholate, a key member of the polyene antifungal class, has been a
cornerstone in the treatment of invasive fungal infections for over five decades. Despite its …
cornerstone in the treatment of invasive fungal infections for over five decades. Despite its …
[PDF][PDF] Amphotericin B: A critical review of its role in antifungal therapy and patient outcomes
I Karunarathna, U Ekanayake, K Gunawardana… - 2024 - researchgate.net
Amphotericin B deoxycholate, a key member of the polyene antifungal class, has been a
cornerstone in the treatment of invasive fungal infections for over five decades. Despite its …
cornerstone in the treatment of invasive fungal infections for over five decades. Despite its …
[PDF][PDF] Amphotericin B and the management of refractory fungal infections: An expert review
I Karunarathna, U Ekanayake, K Gunawardana… - 2024 - researchgate.net
Amphotericin B deoxycholate, a key member of the polyene antifungal class, has been a
cornerstone in the treatment of invasive fungal infections for over five decades. Despite its …
cornerstone in the treatment of invasive fungal infections for over five decades. Despite its …
Toxic eburicol accumulation drives the antifungal activity of azoles against Aspergillus fumigatus
H Elsaman, E Golubtsov, S Brazil, N Ng… - Nature …, 2024 - nature.com
Azole antifungals inhibit the sterol C14-demethylase (CYP51/Erg11) of the ergosterol
biosynthesis pathway. Here we show that the azole-induced synthesis of fungicidal cell wall …
biosynthesis pathway. Here we show that the azole-induced synthesis of fungicidal cell wall …
Delineation of the Direct Contribution of Candida auris ERG11 Mutations to Clinical Triazole Resistance
Resistance to fluconazole is one of clinical characteristics most frequently challenging the
treatment of invasive Candida auris infections, and is observed among> 90% of all …
treatment of invasive Candida auris infections, and is observed among> 90% of all …
Mechanisms of triazole resistance in Aspergillus fumigatus
The ubiquitous fungal pathogen Aspergillus fumigatus is the primary cause of opportunistic
mould infections in humans. Aspergilli disseminate via asexual conidia passively travelling …
mould infections in humans. Aspergilli disseminate via asexual conidia passively travelling …
Citizen Science Surveillance of Triazole-Resistant Aspergillus fumigatus in United Kingdom Residential Garden Soils
JMG Shelton, R Collins, CB Uzzell… - Applied and …, 2022 - Am Soc Microbiol
Compost is an ecological niche for Aspergillus fumigatus due to its role as a decomposer of
organic matter and its ability to survive the high temperatures associated with the …
organic matter and its ability to survive the high temperatures associated with the …
Application of antimicrobial, potential hazard and mitigation plans
The tremendous rise in the consumption of antimicrobial products had aroused global
concerns, especially in the midst of pandemic COVID-19. Antimicrobial resistance has been …
concerns, especially in the midst of pandemic COVID-19. Antimicrobial resistance has been …