Electrochemical late-stage functionalization

Y Wang, S Dana, H Long, Y Xu, Y Li… - Chemical …, 2023 - ACS Publications
Late-stage functionalization (LSF) constitutes a powerful strategy for the assembly or
diversification of novel molecular entities with improved physicochemical or biological …

Cooperative coupling of oxidative organic synthesis and hydrogen production over semiconductor-based photocatalysts

MY Qi, M Conte, M Anpo, ZR Tang, YJ Xu - Chemical Reviews, 2021 - ACS Publications
Merging hydrogen (H2) evolution with oxidative organic synthesis in a semiconductor-
mediated photoredox reaction is extremely attractive because the clean H2 fuel and high …

Electroreductive Cross‐Electrophile Coupling (eXEC) Reactions

Y Liu, P Li, Y Wang, Y Qiu - Angewandte Chemie, 2023 - Wiley Online Library
Electrochemistry utilizes electrons as a potent, controllable, and traceless alternative to
chemical oxidants or reductants, and typically offers a more sustainable option for achieving …

The Rise of Boron-Containing Compounds: Advancements in Synthesis, Medicinal Chemistry, and Emerging Pharmacology

RJ Grams, WL Santos, IR Scorei, A Abad-García… - Chemical …, 2024 - ACS Publications
Boron-containing compounds (BCC) have emerged as important pharmacophores. To date,
five BCC drugs (including boronic acids and boroles) have been approved by the FDA for …

Cross-Electrophile Coupling: Principles, Methods, and Applications in Synthesis

LE Ehehalt, OM Beleh, IC Priest, JM Mouat… - Chemical …, 2024 - ACS Publications
Cross-electrophile coupling (XEC), defined by us as the cross-coupling of two different σ-
electrophiles that is driven by catalyst reduction, has seen rapid progression in recent years …

Boron insertion into alkyl ether bonds via zinc/nickel tandem catalysis

H Lyu, I Kevlishvili, X Yu, P Liu, G Dong - Science, 2021 - science.org
Mild methods to cleave the carbon-oxygen (C− O) bond in alkyl ethers could simplify
chemical syntheses through the elaboration of these robust, readily available precursors …

Cu-catalysed enantioselective radical heteroatomic S–O cross-coupling

YF Cheng, ZL Yu, Y Tian, JR Liu, HT Wen, NC Jiang… - Nature Chemistry, 2023 - nature.com
The transition-metal-catalysed cross-coupling reaction has established itself as one of the
most reliable and practical synthetic tools for the efficient construction of carbon …

A General Three-Component Alkyl Petasis Boron–Mannich Reaction

C Hu, J Tsien, SJ Chen, M Kong… - Journal of the …, 2024 - ACS Publications
Aryl amines are one of the most common moieties in biologically active molecules, and
approximately 37% of drug candidates contain aromatic amines. Recent advancements in …

Mechanistic views and computational studies on transition-metal-catalyzed reductive coupling reactions

A Duan, F Xiao, Y Lan, L Niu - Chemical Society Reviews, 2022 - pubs.rsc.org
Transition-metal-catalyzed reductive coupling reactions have been considered as a
powerful tool to convert two electrophiles into value-added products. Numerous related …

[HTML][HTML] Hydroelementation of diynes

J Walkowiak, J Szyling, A Franczyk… - Chemical Society …, 2022 - pubs.rsc.org
This review highlights the hydroelementation reactions of conjugated and separated diynes,
which depending on the process conditions, catalytic system, as well as the type of reagents …