Previous studies have suggested that migraine is a risk factor for brain lesions, but
methodological issues hampered drawing definite conclusions. Therefore, we initiated the …

Primary headache disorders encompass a heterogeneous group of neurologic disorders
that cause recurrent or persistent head pain without any clear underlying cause. The …

Background and Purpose—This guideline provides an overview of the evidence on
established and emerging risk factors for stroke to provide evidence-based …

Objective: Cortical spreading depression (CSD) has long been implicated in migraine
attacks that begin with visual aura. Having shown that a wave of CSD can trigger long …

Migraine and stroke are two common and heterogeneous neurovascular disorders with
complex relations. Data show no firm association between stroke and migraine without aura …

Migraine is a prevalent primary headache disorder and is usually considered as benign.
However, structural and functional changes in the brain of individuals with migraine have …

Differentiating bipolar disorder (BD) from recurrent unipolar depression (UD) is a major
clinical challenge. Main reasons for this include the higher prevalence of depressive relative …

Objective To evaluate the association of overall and specific headaches with volume of
white matter hyperintensities, brain infarcts, and cognition. Design Population based, cross …

Background and Purpose—Several studies have assessed the possible increased risk of
hemorrhagic stroke in migraineurs, drawing differing conclusions. No meta-analysis on the …

Migraine is currently conceptualized as a chronic disease with episodic manifestations, with
attacks that increase in frequency in a subgroup (migraine transformation or progression) …