[HTML][HTML] Regulation of nicotinic acetylcholine receptors by post-translational modifications
JF Chrestia, O Turani, NR Araujo, G Hernando… - Pharmacological …, 2023 - Elsevier
Nicotinic acetylcholine receptors (nAChRs) comprise a family of pentameric ligand-gated ion
channels widely distributed in the central and peripheric nervous system and in non …
channels widely distributed in the central and peripheric nervous system and in non …
The concept of allosteric modulation: an overview
JP Changeux - Drug Discovery Today: Technologies, 2013 - Elsevier
A brief historical overview of the concept of allosteric interaction is presented together with
the different kinds of allosteric control recognized, in the past decades, with the model …
the different kinds of allosteric control recognized, in the past decades, with the model …
Nicotinic modulation of descending pain control circuitry
IC Umana, CA Daniele, BA Miller, C Abburi… - Pain, 2017 - journals.lww.com
Along with the well-known rewarding effects, activation of nicotinic acetylcholine receptors
(nAChRs) can also relieve pain, and some nicotinic agonists have analgesic efficacy similar …
(nAChRs) can also relieve pain, and some nicotinic agonists have analgesic efficacy similar …
[HTML][HTML] Protein kinase A modulation of CaV1.4 calcium channels
The regulation of L-type Ca2+ channels by protein kinase A (PKA) represents a crucial
element within cardiac, skeletal muscle and neurological systems. Although much work has …
element within cardiac, skeletal muscle and neurological systems. Although much work has …
Adenosine receptors and muscarinic receptors cooperate in acetylcholine release modulation in the neuromuscular synapse
Adenosine receptors (AR s) are present in the motor terminals at the mouse neuromuscular
junction. AR s and the presynaptic muscarinic acetylcholine receptors (mAChR s) share the …
junction. AR s and the presynaptic muscarinic acetylcholine receptors (mAChR s) share the …
Functional interaction between pre‐synaptic α6β2‐containing nicotinic and adenosine A2A receptors in the control of dopamine release in the rat striatum
P Garção, EC Szabó, S Wopereis… - British Journal of …, 2013 - Wiley Online Library
Background and Purpose Pre‐synaptic nicotinic ACh receptors (nAChRs) and adenosine
A2A receptors (A2ARs) are involved in the control of dopamine release and are putative …
A2A receptors (A2ARs) are involved in the control of dopamine release and are putative …
Imidacloprid, a neonicotinoid insecticide, facilitates tyrosine hydroxylase transcription and phenylethanolamine N-methyltransferase mRNA expression to enhance …
I Kawahata, T Yamakuni - Toxicology, 2018 - Elsevier
Imidacloprid is a neonicotinoid insecticide acting as an agonist of nicotinic acetylcholine
receptors (nAChRs) in the target insects. However, questions about the safety to mammals …
receptors (nAChRs) in the target insects. However, questions about the safety to mammals …
Neuroprotective effect of pharmacological postconditioning on cerebral ischaemia–reperfusion-induced injury in mice
Objectives To investigate the mechanism of neuroprotection rendered via pharmacological
postconditioning in cerebral ischaemia–reperfusion-induced injury in mice. Methods …
postconditioning in cerebral ischaemia–reperfusion-induced injury in mice. Methods …
Ethanol-induced motor impairment mediated by inhibition of α7 nicotinic receptors
J McDaid, C Abburi, SL Wolfman… - Journal of …, 2016 - Soc Neuroscience
Nicotine and ethanol (EtOH) are among the most widely co-abused substances, and
nicotinic acetylcholine receptors (nAChRs) contribute to the behavioral effects of both drugs …
nicotinic acetylcholine receptors (nAChRs) contribute to the behavioral effects of both drugs …
[HTML][HTML] Nicotinic acetylcholine receptors (nAChRs) are expressed in Trpm5 positive taste receptor cells (TRCs)
J Qian, S Mummalaneni, JR Grider, MI Damaj, V Lyall - PloS one, 2018 - journals.plos.org
Nicotine evokes chorda tympani (CT) taste nerve responses and an aversive behavior in
Trpm5 knockout (KO) mice. The agonists and antagonists of nicotinic acetylcholine receptors …
Trpm5 knockout (KO) mice. The agonists and antagonists of nicotinic acetylcholine receptors …