Immunoporosis: role of innate immune cells in osteoporosis
Osteoporosis or porous bone disorder is the result of an imbalance in an otherwise highly
balanced physiological process known as 'bone remodeling'. The immune system is …
balanced physiological process known as 'bone remodeling'. The immune system is …
[HTML][HTML] Targeting proteostasis network in osteoporosis: pathological mechanisms and therapeutic implications
C Ma, R Yu, J Li, J Chao, P Liu - Ageing Research Reviews, 2023 - Elsevier
As the most common bone disease, osteoporosis (OP) increases bone fragility and makes
patients more vulnerable to the threat of osteoporotic fractures. With the ageing population in …
patients more vulnerable to the threat of osteoporotic fractures. With the ageing population in …
[HTML][HTML] Black phosphorus biomaterials for photo-controlled bone tissue engineering
L Tan, M Li, Z Luo, K Cai, Y Hu - Composites Part B: Engineering, 2022 - Elsevier
Over the past decades, black phosphorus (BP) emerges as an effective photothermal
material with clinically favorable biocompatibility and biodegradation that receives broad …
material with clinically favorable biocompatibility and biodegradation that receives broad …
Multi-omics data integration for identifying osteoporosis biomarkers and their biological interaction and causal mechanisms
Osteoporosis is characterized by low bone mineral density (BMD). The advancement of high-
throughput technologies and integrative approaches provided an opportunity for …
throughput technologies and integrative approaches provided an opportunity for …
Endocrine, Metabolic, and Immune Pathogenesis of Postmenopausal Osteoporosis. Is there a Therapeutic Role in Natural Products?
G Lisco, D Triggiani, VA Giagulli… - … Metabolic & Immune …, 2023 - ingentaconnect.com
Background: Bone health relies on the equilibrium between resorption and new bone
generation. Postmenopausal osteoporosis depends on estrogen deficiency which favorite …
generation. Postmenopausal osteoporosis depends on estrogen deficiency which favorite …
Inhibition of C5AR1 impairs osteoclast mobilization and prevents bone loss
C Pimenta-Lopes, C Sánchez-de-Diego, A Deber… - Molecular Therapy, 2023 - cell.com
Age-related and chemotherapy-induced bone loss depends on cellular senescence and the
cell secretory phenotype. However, the factors secreted in the senescent microenvironment …
cell secretory phenotype. However, the factors secreted in the senescent microenvironment …
Proteomic changes of osteoclast differentiation in rheumatoid and psoriatic arthritis reveal functional differences
OT Kovács, E Tóth, O Ozohanics… - Frontiers in …, 2022 - frontiersin.org
Background Osteoclasts play a crucial role in the maintenance, repair, and remodeling of
bones of the adult vertebral skeleton due to their bone resorption capability. Rheumatoid …
bones of the adult vertebral skeleton due to their bone resorption capability. Rheumatoid …
MAP Kinase driven actomyosin rearrangement is a crucial regulator of monocyte to macrophage differentiation
Rearrangement of actin cytoskeleton correlates significantly with the immune responses as
the perturbation of cytoskeletal dynamics leads to many immune deficiencies. Mechanistic …
the perturbation of cytoskeletal dynamics leads to many immune deficiencies. Mechanistic …
[HTML][HTML] An updated overview of the search for biomarkers of osteoporosis based on human proteomics
XY Wang, RZ Zhang, YK Wang, S Pan, SM Yun… - Journal of Orthopaedic …, 2024 - Elsevier
Osteoporosis is a chronic metabolic disease that increases bone fragility and, leads to
severe osteoporotic fractures. In recent years, the use of high-throughput omics to explore …
severe osteoporotic fractures. In recent years, the use of high-throughput omics to explore …
[HTML][HTML] Proteomic Biomarkers Associated with Low Bone Mineral Density: A Systematic Review
A Becerra-Cervera, AD Argoty-Pantoja… - International Journal of …, 2024 - mdpi.com
Osteoporosis is a globally relevant public health issue. Our study aimed to summarize the
knowledge on the proteomic biomarkers for low bone mineral density over the last years. We …
knowledge on the proteomic biomarkers for low bone mineral density over the last years. We …