Nonalcoholic fatty liver disease (NAFLD) has emerged as the most common chronic liver
disease worldwide and is strongly associated with the presence of oxidative stress …

Aging has been linked to several degenerative processes that, through the accumulation of
molecular and cellular damage, can progressively lead to cell dysfunction and organ failure …

In the brain, mitochondrial metabolism has been largely associated with energy production,
and its dysfunction is linked to neuronal cell loss. However, the functional role of …

Enlarged fat cells in obese adipose tissue diminish capacity to store fat and are resistant to
the anti-lipolytic effect of insulin. Insulin resistance (IR)-associated S-nitrosylation of insulin …

▪ Abstract The production of reactive oxygen species (ROS), such as O2− and H2O2, is an
unavoidable consequence of aerobic metabolism. In plant cells the mitochondrial electron …

We sought to understand the relationship between reactive oxygen species (ROS) and the
mitochondrial permeability transition (MPT) in cardiac myocytes based on the observation of …

Reactive oxygen species (ROS) are recognized both as damaging molecules and
intracellular signaling entities. In addition to its role in ATP generation, the mitochondrial …

The recent knowledge on mitochondria as the substantial source of reactive oxygen species,
namely superoxide and hydrogen peroxide efflux from mitochondria, is reviewed, as well as …

Several lines of evidence indicate that mitochondrial reactive oxygen species (ROS)
generation is the major source of oxidative stress in the cell. It has been shown that ROS …

The mitochondrion is a major source of reactive oxygen species (ROS). Superoxide (O 2•−)
is generated under specific bioenergetic conditions at several sites within the electron …