Oxytocin, cortisol and 3, 4-methylenedioxymethamphetamine: neurohormonal aspects of recreational 'ecstasy'

AC Parrott - Behavioural Pharmacology, 2016 - journals.lww.com
Abstract Most research into 3, 4-methylenedioxymethamphetamine (MDMA) has debated its
psychobiological effects in relation to neurotransmission. This article debates the …

Of mice and men on MDMA: A translational comparison of the neuropsychobiological effects of 3, 4-methylenedioxymethamphetamine ('Ecstasy')

MA Aguilar, MP García-Pardo, AC Parrott - Brain research, 2020 - Elsevier
Abstract MDMA (3, 4-methylendioxymethamphetamine), also known as Ecstasy, is a
stimulant drug recreationally used by young adults usually in dance clubs and raves. Acute …

Role of NMDA and AMPA glutamatergic receptors in the effects of social defeat on the rewarding properties of MDMA in mice

MP García‐Pardo, J Miñarro, M Llansola… - European Journal of …, 2019 - Wiley Online Library
Exposure to social stress alters the response to drugs of abuse of experimental animals.
Changes in the glutamatergic system seem to play a role in the effects of social defeat stress …

Dextromethorphan moderates reward deficiency associated with central serotonin transporter availability in 3, 4-methylenedioxy-methamphetamine-treated animals

CH Chiu, KH Ma, EYK Huang, HW Chang… - Journal of the …, 2024 - journals.lww.com
Background: The neurotoxicity of 3, 4-methylenedioxy-methamphetamine (MDMA) to the
serotonergic system is well-documented. Dextromethorphan (DM), an antitussive drug …

Role of nitric oxide pathway in the conditioned rewarding effects of MDMA in mice

MP García-Pardo, M Rodríguez-Arias, J Miñarro… - Behavioural brain …, 2017 - Elsevier
It is estimated that 2.1 million young adults used MDMA/Ecstasy in the last year in Europe.
Vulnerable subjects can develop dependence after MDMA abuse but currently there does …

The biology of nitric oxide signaling and MDMA

MP García-Pardo, C Calpe-López… - Handbook of Substance …, 2022 - Springer
It has been proposed that a close interaction between nitric oxide (NO), dopamine, and
glutamate in the brain circuits of reward is key to the development of an addictive disorder …

Role of AMPA glutamate receptors in the conditioned rewarding effects of MDMA in mice

MP García-Pardo, J Miñarro, MA Aguilar - Behavioural Brain Research, 2018 - Elsevier
Currently, there is not an effective treatment for 3, 4-methylenedioxymethamphetamine
(MDMA) dependence but pharmacotherapies targeting glutamate neurotransmission are a …

Therapeutische toepassingen van psychedelica: Kansen, uitdagingen en zorginnovatie voor behandelresistente psychiatrische aandoeningen

R Schoevers, JJ Breeksema, R Boesjes - 2023 - research.rug.nl
An estimated 200,000 people in the Netherlands with a psychiatric disorder continue to have
serious mental health problems despite regular treatment. These chronic and difficult-to-treat …

[引用][C] ФЕДЕРАЛЬНОЕ АГЕНТСТВО НАУЧНЫХ ОРГАНИЗАЦИЙ РОССИЙСКОЙ ФЕДЕРАЦИИ ФЕДЕРАЛЬНОЕ ГОСУДАРСТВЕННОЕ БЮДЖЕТНОЕ НАУЧНОЕ …

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