Phthalates (diesters of phthalic acid) are widely used as plasticizers and additives in many
consumer products. Laboratory animal studies have reported the endocrine-disrupting and …

The onset of puberty in adolescents and whether it is related to obesity is an ongoing topic
for debate. Epidemiological cross-sectional and longitudinal studies show a shift towards …

Wildlife has often presented and suggested the effects of endocrine disrupting chemicals
(EDCs). Animal studies have given us an important opportunity to understand the …

There is growing interest in the possible health threat posed by endocrine-disrupting
chemicals (EDCs), which are substances in our environment, food, and consumer products …

STUDY QUESTION Are in-utero or peripubertal exposures to phthalates, parabens and
other phenols found in personal care products associated with timing of pubertal onset in …

Adolescence is a time of dramatic changes including rapid physical growth, the onset of
sexual maturation, the activation of new drives and motivations, and a wide array of social …

The decline in age at puberty in the general population has been paralleled by an increase
in the number of girls referred for evaluation of precocious puberty (PP). In 1999, The …

BACKGROUND AND OBJECTIVES: There is growing evidence of pubertal maturation
occurring at earlier ages, with many studies based on cross-sectional observations. This …

OBJECTIVE. Recent publications showing unexpectedly early breast development in
American girls created debate worldwide. However, secular trend analyses are often limited …

Exposure to exogenous chemicals can affect endocrine function at multiple sites and
through numerous specific modes of action, which may have far-reaching effects on human …