Malaria chemoprevention and drug resistance: a review of the literature and policy implications
CV Plowe - Malaria Journal, 2022 - Springer
Chemoprevention strategies reduce malaria disease and death, but the efficacy of anti-
malarial drugs used for chemoprevention is perennially threatened by drug resistance. This …
malarial drugs used for chemoprevention is perennially threatened by drug resistance. This …
High-throughput Plasmodium falciparum hrp2 and hrp3 gene deletion typing by digital PCR to monitor malaria rapid diagnostic test efficacy
Most rapid diagnostic tests for Plasmodium falciparum malaria target the Histidine-Rich
Proteins 2 and 3 (HRP2 and HRP3). Deletions of the hrp2 and hrp3 genes result in false …
Proteins 2 and 3 (HRP2 and HRP3). Deletions of the hrp2 and hrp3 genes result in false …
[HTML][HTML] Genetic surveillance for monitoring the impact of drug use on Plasmodium falciparum populations
YD Ndiaye, DL Hartl, D McGregor, A Badiane… - International Journal for …, 2021 - Elsevier
The use of antimalarial drugs is an effective strategy in the fight against malaria. However,
selection of drug resistant parasites is a constant threat to the continued use of this …
selection of drug resistant parasites is a constant threat to the continued use of this …
[HTML][HTML] Plasmodium falciparum infection and naturally acquired immunity to malaria antigens among Ghanaian children in Northern Ghana
Z Seidu, H Lamptey, M Lopez-Perez, NO Whittle… - Parasite epidemiology …, 2023 - Elsevier
Background The surge in malaria cases and deaths in recent years, particularly in Africa,
despite the widespread implementation of malaria-control measures could be due to …
despite the widespread implementation of malaria-control measures could be due to …
Diagnostic performance of an ultrasensitive HRP2-based malaria rapid diagnostic test kit used in surveys of afebrile people living in Southern Ghana
Abstract Background The Alere™ Malaria Ag Pf Ultra-sensitive RDT (UsmRDT) kit is an
HRP2-based malaria rapid diagnostic test (RDT) with enhanced sensitivity relative to the SD …
HRP2-based malaria rapid diagnostic test (RDT) with enhanced sensitivity relative to the SD …
Distribution of Plasmodium falciparum K13 gene polymorphisms across transmission settings in Ghana
Malaria is a significant global health concern, with a majority of cases in Sub-Saharan
African nations. Numerous antimalarial drugs have been developed to counter the rampant …
African nations. Numerous antimalarial drugs have been developed to counter the rampant …
[HTML][HTML] Biomarker of Anopheles exposure in Ghanaian children with hemoglobin S and C
Heterozygous carriers of hemoglobin S and C (HbAS and HbAC) have a reduced risk of
severe malaria but are not protected from Plasmodium falciparum infection, suggesting that …
severe malaria but are not protected from Plasmodium falciparum infection, suggesting that …
[HTML][HTML] Genetic variations of Plasmodium falciparum circumsporozoite protein and the impact on interactions with human immunoproteins and malaria vaccine …
In October 2021, the world's first malaria vaccine RTS, S was endorsed by WHO for broad
use in children, despite its low efficacy. This study examined polyclonal infections and the …
use in children, despite its low efficacy. This study examined polyclonal infections and the …
Seasonal malaria chemoprevention and the spread of Plasmodium falciparum quintuple-mutant parasites resistant to sulfadoxine–pyrimethamine: a modelling study
Background Seasonal malaria chemoprevention (SMC) with sulfadoxine–pyrimethamine
plus amodiaquine prevents millions of clinical malaria cases in children younger than 5 …
plus amodiaquine prevents millions of clinical malaria cases in children younger than 5 …
[HTML][HTML] Malaria surveillance amongst pregnant women attending antenatal care in private hospitals in Onitsha metropolis, South Eastern Nigeria
MN Ikegbunam, C Uba, J Flügge, H Abone… - MalariaWorld …, 2022 - ncbi.nlm.nih.gov
Background Recent reports suggest that pregnant women living in holoendemic regions of
sub-Sahara Africa die in great numbers annually due to malaria disease resulting from their …
sub-Sahara Africa die in great numbers annually due to malaria disease resulting from their …