Importance Ulcerative colitis (UC) is a chronic inflammatory condition of the colon, with a
prevalence exceeding 400 per 100 000 in North America. Individuals with UC have a lower …

The incidence and prevalence of Crohn's disease (CD) is rising globally. Patients with
moderate to severe CD are at high risk for needing surgery and hospitalization and for …

Background & Aims Biomarkers are used frequently for noninvasive monitoring and
treatment decision making in the management of patients with ulcerative colitis (UC). This …

The burden of inflammatory bowel disease (IBD) in older adults (ie, aged over 60 years old)
is increasing due to a combination of an ageing population with compounding prevalence of …

Objectives Cannabis-based medicinal products (CBMPs) have shown promising preclinical
activity in inflammatory bowel disease (IBD). However, clinical trials have not demonstrated …

Over the past decades, there has been a rapid increase in the incidence and prevalence of
inflammatory bowel disease (IBD) in Asia. The natural history of IBD in Asian patients could …

Abstract Background and Aims Perianal Crohn's disease (pCD) is a potentially severe
phenotype of CD. We conducted a systematic review with meta-analysis to estimate …

Importance Observational comparative effectiveness studies can inform the positioning of
biologic therapies for older patients with inflammatory bowel disease (IBD) who are …

High levels of proinflammatory cytokines, macrophage polarization status and immune-
mediated angiogenesis play pivotal roles in the pathogenesis of inflammatory bowel …

Crohn's disease (CD) is an inflammatory bowel disease (IBD) sub-type characterized by
transmural chronic inflammation of the gastrointestinal tract. Research indicates a complex …