The advancements in technology and manufacturing processes have allowed the
development of new derivatives, biosimilar or advanced improved versions for approved …

Hepatocellular carcinoma (HCC) is one of the major cancers in the world. There is a striking
variation in HCC incidence rates between various countries, with a highest‐to‐lowest ratio of …

SUMMARY Epstein-Barr virus (EBV) DNA measurement is being incorporated into routine
medical practice to help diagnose, monitor, and predict posttransplant lymphoproliferative …

Telomeres and adjacent subtelomeric regions are packaged as heterochromatin in many
organisms. The heterochromatic features include DNA methylation, histones H3-Lys9 …

Epstein-Barr virus (EBV) is closely associated with the generation of various tumors,
including Burkitt's lymphoma. Human resting B cells from peripheral blood are easily …

It is generally assumed that human differentiated cells have a limited life-span and
proliferation capacity in vivo, and that genetic modifications are a prerequisite for their …

Marek's disease virus (MDV) is a herpesvirus of chickens that induces T lymphomas and
tumors within 4 to 5 weeks of infection. Although the ability of MDV to induce tumors was …

Human tumor viruses are responsible for one-fifth of all cancers worldwide. These viruses
have evolved multiple strategies to evade immune defenses and to persist in the host by …

The majority of patients tolerate radiotherapy well, but some of them suffer from severe side
effects. To find genes possibly predictive for radiosensitivity, mRNA profiles were generated …

In contrast to other tumor suppressor genes, the majority of TP53 alterations are missense
mutations. We have previously reported that in the Li–Fraumeni syndrome (LFS), germline …