It is well known that phenotype of animals may be modified by the nutritional modulations
through epigenetic mechanisms. As a key and central component of epigenetic network …

A wide range of maternal exposures—undernutrition, obesity, diabetes, stress and infection—
are associated with an increased risk of metabolic disease in offspring. Developmental …

Objective We examined the impact of maternal low-dose aspartame and stevia consumption
on adiposity, glucose tolerance, gut microbiota and mesolimbic pathway in obese dams and …

The obesity epidemic is a leading cause of health problems in the United States, increasing
the risk of cardiovascular, endocrine, and psychiatric diseases. Although many people lose …

This review discusses the long-term effects of early-life environment on epileptogenesis,
epilepsy, and neuropsychiatric comorbidities with an emphasis on the absence epilepsy …

Rationale Preclinical studies report that free access to a high-fat diet (HFD) alters the
response to psychostimulants. Objectives The aim of the present study was to examine how …

Binge eating disorder is the most common eating disorder, but its underlying etiology is
poorly understood. Both humans and animals exhibit binge-like intake of highly-palatable …

Perinatal junk food exposure increases the preference for palatable diets in juvenile and
adult rat offspring. Previous studies have implicated reduced sensitivity of the opioid …

Metabolic status impacts on the emotional brain to induce behavior that maintains energy
balance. While hunger suppresses the fear circuitry to promote explorative food-seeking …

Roux-en-Y gastric bypass surgery (RYGB) is the most common and effective weight loss
procedure for severe obesity. However, a significant increase in addictive behaviors and …