[HTML][HTML] Targeting mitophagy for depression amelioration: a novel therapeutic strategy
W Xu, W Gao, Y Guo, F Xue, L Di, S Fang… - Frontiers in …, 2023 - frontiersin.org
Major depressive disorder is a global psychiatric condition characterized by persistent low
mood and anhedonia, which seriously jeopardizes the physical and mental well-being of …
mood and anhedonia, which seriously jeopardizes the physical and mental well-being of …
Dysregulation of mitochondrial dynamics, mitophagy and apoptosis in major depressive disorder: Does inflammation play a role?
Recent studies have suggested that mitochondrial dysfunction and dysregulated
neuroinflammatory pathways are involved in the pathophysiology of major depressive …
neuroinflammatory pathways are involved in the pathophysiology of major depressive …
[HTML][HTML] The relationship between stress, inflammation, and depression
IB Kim, JH Lee, SC Park - Biomedicines, 2022 - mdpi.com
A narrative review about the relationship between stress, inflammation, and depression is
made as follows: Chronic stress leads to various stress-related diseases such as …
made as follows: Chronic stress leads to various stress-related diseases such as …
[HTML][HTML] Shared genetic liability and causal associations between major depressive disorder and cardiovascular diseases
F Zhang, H Cao, A Baranova - Frontiers in cardiovascular medicine, 2021 - frontiersin.org
Major depressive disorder (MDD) is phenotypically associated with cardiovascular diseases
(CVD). We aim to investigate mechanisms underlying relationships between MDD and CVD …
(CVD). We aim to investigate mechanisms underlying relationships between MDD and CVD …
Glial fibrillary acidic protein as blood biomarker for differential diagnosis and severity of major depressive disorder
P Steinacker, MHDR Al Shweiki, P Oeckl, H Graf… - Journal of psychiatric …, 2021 - Elsevier
Neuroinflammation has been connected to the pathophysiology of major depressive
disorder (MDD) and neurochemical biomarkers of glial pathology could aid the diagnosis …
disorder (MDD) and neurochemical biomarkers of glial pathology could aid the diagnosis …
[HTML][HTML] MX2: Identification and systematic mechanistic analysis of a novel immune-related biomarker for systemic lupus erythematosus
XW Meng, ZL Cheng, ZY Lu, YN Tan, XY Jia… - Frontiers in …, 2022 - frontiersin.org
Background Systemic lupus erythematosus (SLE) is an autoimmune disease that involves
multiple organs. However, the current SLE-related biomarkers still lack sufficient sensitivity …
multiple organs. However, the current SLE-related biomarkers still lack sufficient sensitivity …
Lysosomal dysfunction is associated with NLRP3 inflammasome activation in chronic unpredictable mild stress-induced depressive mice
MM Li, X Wang, XD Chen, HL Yang, HS Xu… - Behavioural Brain …, 2022 - Elsevier
NLRP3 inflammasome pathway-mediated inflammatory response is closely associated with
depression. Increasing attention has been recently paid to the links between autophagy and …
depression. Increasing attention has been recently paid to the links between autophagy and …
[HTML][HTML] Abnormal reginal homogeneity in left anterior cingulum cortex and precentral gyrus as a potential neuroimaging biomarker for first-episode major depressive …
Y Song, C Huang, Y Zhong, X Wang, G Tao - Frontiers in Psychiatry, 2022 - frontiersin.org
Objective There is no objective method to diagnose major depressive disorder (MDD). This
study explored the neuroimaging biomarkers using the support vector machine (SVM) …
study explored the neuroimaging biomarkers using the support vector machine (SVM) …
[HTML][HTML] Identification of mitophagy-related biomarkers and immune infiltration in major depressive disorder
J Zhang, S Xie, R Xiao, D Yang, Z Zhan, Y Li - BMC genomics, 2023 - Springer
Background Major depressive disorder (MDD) is a life-threatening and debilitating mental
health condition. Mitophagy, a form of selective autophagy that eliminates dysfunctional …
health condition. Mitophagy, a form of selective autophagy that eliminates dysfunctional …
Perinatal SSRI exposure disrupts G protein-coupled receptor BAI3 in developing dentate gyrus and adult emotional behavior: relevance to psychiatric disorders
KA Unroe, ME Glover, EA Shupe, N Feng, SM Clinton - Neuroscience, 2021 - Elsevier
Selective serotonin reuptake inhibitor (SSRI) antidepressants are widely prescribed to
pregnant women suffering with depression, although the long-term impact of these …
pregnant women suffering with depression, although the long-term impact of these …