Polyhydroxyalkanoates (PHAs) are diverse biopolyesters produced by numerous
microorganisms and have attracted much attention as a substitute for petroleum-based …

Because of their function of catalyzing the rearrangement of the carbon chains, thiolases
have attracted increasing attentions over the past decades. The 3-ketoacyl-CoA thiolase …

An engineered reversal of the β-oxidation cycle was exploited to demonstrate its utility for
the synthesis of medium chain (6–10-carbons) ω-hydroxyacids and dicarboxylic acids from …

Formation of carbon–carbon bonds via Claisen condensation catalyzed by thiolase
generates a diverse range of carbon frameworks in biosynthetic chemistry. During catalysis …

The caproate-producing bacterium, Megasphaera hexanoica, metabolizes fructose to
produce C2~ C8 carbon-chain carboxylic acids using various electron acceptors. In …

Polyketides found in nature originate from backbones synthesized through iterative
decarboxylative Claisen condensations catalysed by polyketide synthases (PKSs) …

Decanol has great value in the pharmaceutical and fragrance industries and plays an
important role in the chemical industry. In this study, we engineered Escherichia coli to …

Medium-chain length methyl ketones are potential blending fuels due to their cetane
numbers and low melting temperatures. Biomanufacturing offers the potential to produce …

Thiolase is essential in the first step of synthesizing many value-added biochemicals.
However, only a few feasible THLs have been reported, and a limited understanding of …

The legal cannabis market worldwide is facing new challenges regarding innovation in the
production of cannabinoid-based drugs. The usual cannabinoid production involves …