[HTML][HTML] The Role of Biomarkers in the Diagnosis and Prognosis of Different Stages of Melanoma

JN Nwafor, BE Torere, E Agu, L Kadiku, T Ogunyemi… - Cureus, 2023 - ncbi.nlm.nih.gov
Melanoma is a skin cancer arising from melanocytes, the cells responsible for synthesizing
melanin pigment, which gives the skin its color. Early diagnosis and treatment of melanoma …

Secretogranin II influences the assembly and function of MHC class I in melanoma

T Steinfass, J Poelchen, Q Sun, G Mastrogiulio… - … hematology & oncology, 2023 - Springer
Melanoma is the deadliest form of skin cancer showing rising incidence over the past years.
New insights into the mechanisms of melanoma progression contributed to the development …

Computer-aided design and synthesis of 3-carbonyl-5-phenyl-1H-pyrazole as highly selective and potent BRAFV600E and CRAF inhibitor

J Kim, B Choi, D Im, H Jung, H Moon… - Journal of Enzyme …, 2019 - Taylor & Francis
BRAF belongs to the upstream portion of the MAPK pathway, which is involved in cell
proliferation and survival. When mutations occur in BRAF, downstream MEK and ERK are …

[HTML][HTML] Establishment of skin cutaneous melanoma prognosis model based on vascular mimicry risk score

Y Wang, L Zou, M Song, J Zong, S Wang, L Meng… - Medicine, 2024 - journals.lww.com
Studies have indicated that Vascular mimicry (VM) could contribute to the unfavorable
prognosis of skin cutaneous melanoma (SKCM). Thus, the objective of this study was to …

Cell-Cycle Synchronization Prior to Radiotherapy: A Mathematical Model of the Use of Gemcitabine on Melanoma Xenografts

F Rentzeperis, B Coleman, D Wallace - AppliedMath, 2024 - mdpi.com
Radiotherapy can differentially affect the phases of the cell cycle, possibly enhancing
suppression of tumor growth, if cells are synchronized in a specific phase. A model is …

Role of non-coding RNA alterations in melanoma

E Broseghini - 2022 - amsdottorato.unibo.it
Cutaneous melanoma (CM) is a potentially lethal form of skin cancer and its most important
histopathologic factor for staging is Breslow thickness (BT). Its correct determination is …