Non-diffracting light wave: fundamentals and biomedical applications

YX Ren, H He, H Tang, KKY Wong - Frontiers in Physics, 2021 - frontiersin.org
The light propagation in the medium normally experiences diffraction, dispersion, and
scattering. Studying the light propagation is a century-old problem as the photons may …

Advances of optical miniscopes for in vivo imaging of neural activity in freely moving animals

K Chen, Z Tian, L Kong - Frontiers in Neuroscience, 2022 - frontiersin.org
To study neural mechanisms of ethologically relevant behaviors including many social
behaviors and navigations, optical miniscopes, which can be carried by the model animals …

Pupil engineering for extended depth-of-field imaging in a fluorescence miniscope

J Greene, Y Xue, J Alido, A Matlock, G Hu… - …, 2023 - spiedigitallibrary.org
Significance Fluorescence head-mounted microscopes, ie, miniscopes, have emerged as
powerful tools to analyze in-vivo neural populations but exhibit a limited depth-of-field (DoF) …

FAMOUS: a fast instrumental and computational pipeline for multiphoton microscopy applied to 3D imaging of muscle ultrastructure

C Lefort, M Chalvidal, A Parenté… - Journal of Physics D …, 2021 - iopscience.iop.org
We present a new instrumental and computational pipeline named FAMOUS: fast algorithm
for three-dimensional (3D) multiphoton microscopy of biomedical structures. This pipeline …

微型化显微成像系统的关键技术及研究进展(特邀)

刘晓宇, 刘紫千, 斯科, 龚薇 - Laser & Optoelectronics Progress, 2024 - opticsjournal.net
摘要神经环路动态功能的解析是当前脑科学领域的重点和难点, 微型化显微成像技术为其研究
提供了重要手段. 相较于双光子荧光成像和光纤光度法, 微型化显微系统能够在模式动物自由 …

High‐speed volumetric imaging in vivo based on structured illumination microscopy with interleaved reconstruction

R Shi, Y Li, L Kong - Journal of Biophotonics, 2021 - Wiley Online Library
Wide‐field fluorescence microscopy (WFFM) is widely adopted in biomedical studies, due to
its high imaging speed over large field‐of‐views. However, WFFM is susceptible to out‐of …

Background inhibited and speed-loss-free volumetric imaging in vivo based on structured-illumination Fourier light field microscopy

J Zhai, R Shi, K Fan, L Kong - Frontiers in Neuroscience, 2022 - frontiersin.org
Benefiting from its advantages in fast volumetric imaging for recording biodynamics, Fourier
light field microscopy (FLFM) has a wide range of applications in biomedical research …

Edof-miniscope: pupil engineering for extended depth-of-field imaging in a fluorescence miniscope

J Greene, Y Xue, J Alido, A Matlock, G Hu, K Kiliç… - bioRxiv, 2022 - biorxiv.org
Extended depth of field (EDoF) microscopy has emerged as a powerful solution to greatly
increase the access into neuronal populations in table-top imaging platforms. Here, we …

采用硅光电倍增管阵列扩展探测实现非线性荧光显微技术中散射光子探测信号的增强

R Shi, C Jin, C Liu, L Kong, AR Shi, AC Jin, AC Liu… - Frontiers, 2021 - jzus.zju.edu.cn
为提高非线性荧光显微技术在活体成像中的信号探测能力, 人们常采用基于非退扫描的背向探测
策略. 然而, 由于生物样本中存在严重散射, 物镜前孔径处大部分荧光光子辐射角度超出物镜收集 …

Enhanced collection of scattered photons in nonlinear fluorescence microscopy by extended epi-detection with a silicon photomultiplier array

R Shi, C Jin, C Liu, L Kong - Frontiers of Information Technology & …, 2021 - Springer
To maximize signal collection in nonlinear optical microscopy, non-descanned epi-detection
is generally adopted for in vivo imaging. However, because of severe scattering in biological …