Red blood cells (RBC) are the most abundant cell in the human body, with a central role in
oxygen transport and its delivery to tissues. However, omics technologies recently revealed …

Red blood cells (RBCs) deformability refers to the cells' ability to adapt their shape to the
dynamically changing flow conditions so as to minimize their resistance to flow. The high red …

Transfusion of red blood cells (RBCs) is one of the most valuable and widespread
treatments in modern medicine. Lifesaving RBC transfusions are facilitated by the cold …

Red blood cell transfusion is a life-saving intervention, and storage is a logistic necessity to
make~ 110 million units available for transfusion every year worldwide. However, storage in …

Background The evolutionary pressure of endemic malaria and other erythrocytic pathogens
has shaped variation in genes encoding erythrocyte structural and functional proteins …

The red blood cell (RBC)-Omics study, part of the larger NHLBI-funded Recipient
Epidemiology and Donor Evaluation Study (REDS-III), aims to understand the genetic …

Over the last decade, the introduction of omics technologies–especially high-throughput
genomics and metabolomics–has contributed significantly to our understanding of the role of …

Background The Red blood cell (RBC) storage lesion results in decreased circulation and
function of transfused RBCs. Elevated oxidant stress and impaired energy metabolism are a …

Red blood cell (RBC) transfusion is a life-saving intervention for millions of trauma patients
every year worldwide. While hemoglobin thresholds are clinically driving the need for RBC …

In the field of transfusion medicine, the clinical relevance of the metabolic markers of the red
blood cell (RBC) storage lesion is incompletely understood. Here, we performed …