Cannabinoid formulations and delivery systems: Current and future options to treat pain
B Stella, F Baratta, C Della Pepa, S Arpicco, D Gastaldi… - Drugs, 2021 - Springer
The field of Cannabis sativa L. research for medical purposes has been rapidly advancing in
recent decades and a growing body of evidence suggests that phytocannabinoids are …
recent decades and a growing body of evidence suggests that phytocannabinoids are …
Conversion technologies for valorization of hemp lignocellulosic biomass for potential biorefinery applications
Fossil fuel supplies are becoming scarce as a result of the growing world's population. The
increasing use of fossil fuels also pose a threat to ecosystem. Renewable energy sources …
increasing use of fossil fuels also pose a threat to ecosystem. Renewable energy sources …
[HTML][HTML] The emerging role of quercetin in the treatment of chronic pain
C Liu, DQ Liu, YK Tian, W Mei, XB Tian… - Current …, 2022 - ncbi.nlm.nih.gov
Despite much research efforts being devoted to designing alternative pharmacological
interventions, chronic pain remains to be an unresolved clinical problem. Quercetin, a …
interventions, chronic pain remains to be an unresolved clinical problem. Quercetin, a …
A sensitive ultrahigh-performance liquid chromatography/tandem mass spectrometry method for the simultaneous analysis of phytocannabinoids and …
Introduction: Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD) are major chemical
constituents of cannabis, which may interact either directly or indirectly with the …
constituents of cannabis, which may interact either directly or indirectly with the …
NAAA-regulated lipid signaling in monocytes controls the induction of hyperalgesic priming in mice
Y Fotio, A Mabou Tagne, E Squire, H Lee… - Nature …, 2024 - nature.com
Circulating monocytes participate in pain chronification but the molecular events that cause
their deployment are unclear. Using a mouse model of hyperalgesic priming (HP), we show …
their deployment are unclear. Using a mouse model of hyperalgesic priming (HP), we show …
Δ9-Tetrahydrocannabinol alleviates hyperalgesia in a humanized mouse model of sickle cell disease
People with sickle cell disease (SCD) often experience chronic pain as well as
unpredictable episodes of acute pain, which significantly affects their quality of life and life …
unpredictable episodes of acute pain, which significantly affects their quality of life and life …
Synergistic antinociceptive effects of concomitant NAAA and peripheral FAAH inhibition
The intracellular lipid amidases, fatty acid amide hydrolase (FAAH) and N-acylethanolamine
acid amidase (NAAA), terminate the actions of anandamide and palmitoylethanolamide …
acid amidase (NAAA), terminate the actions of anandamide and palmitoylethanolamide …
Unraveling brain palmitic acid: Origin, levels and metabolic fate
ME Smith, RP Bazinet - Progress in Lipid Research, 2024 - Elsevier
In the human brain, palmitic acid (16: 0; PAM) comprises nearly half of total brain saturates
and has been identified as the third most abundant fatty acid overall. Brain PAM supports the …
and has been identified as the third most abundant fatty acid overall. Brain PAM supports the …
Cannabis Extract Has a Positive–Immunostimulating Effect through Proteolytic System and Metabolic Compounds of Honey Bee (Apis mellifera) Workers
P Skowronek, Ł Wójcik, A Strachecka - Animals, 2021 - mdpi.com
Simple Summary The aim of our study was to test the immunostimulating effect of a diet with
hemp extract on the resistance of the honey bee (Apis mellifera). The experiment compared …
hemp extract on the resistance of the honey bee (Apis mellifera). The experiment compared …
Chronic pain in dogs and cats: Is there place for dietary intervention with micro-palmitoylethanolamide?
G Della Rocca, D Gamba - Animals, 2021 - mdpi.com
Simple Summary Chronic pain is being increasingly recognized and addressed in small
animal practice. The recent recognition that inability to communicate does not negate the …
animal practice. The recent recognition that inability to communicate does not negate the …