Recent advances on trauma management from the prehospital setting to in hospital care led
to a better surviving severe trauma rate. Mortality from exsanguination remains the first …

Blood clots, which are composed of blood cells and a stabilizing mesh of fibrin fibers, are
critical in cessation of bleeding following injury. However, their action is transient and after …

(1) Background: Liver transplantation (LT) is associated with significant hemorrhage and
massive transfusions. Fibrinogen replacement has a key role in treating massive bleeding …

Key questions in bleeding management are “Why does my patient bleed?” and “How to fix
it?” To answer the first question, the high negative predictive value of viscoelastic testing can …

Real-world utilization of 4-factor prothrombin complex concentrate (4F-PCC) and plasma for
the management of oral anticoagulant (OAC)-associated bleeding in US trauma hospitals …

Background: Hypofibrinogenemia has been shown to predict massive transfusion and is
associated with higher mortality in severely injured patients. However, the role of empiric …

A doença trauma é a principal causa de morte da população brasileira, na faixa etária entre
1 a 49 anos, desconsiderando-se os recentes impactos da pandemia por covid-19 (BRASIL …