[HTML][HTML] Nicotinic receptors in the brain: links between molecular biology and behavior
Molecular cloning has elucidated the sequence of a family of acetylcholine receptor subunits
that are activated by nicotine. Subsequent studies on the localization of individual subunits …
that are activated by nicotine. Subsequent studies on the localization of individual subunits …
The subtypes of nicotinic acetylcholine receptors on dopaminergic terminals of mouse striatum
SR Grady, O Salminen, DC Laverty, P Whiteaker… - Biochemical …, 2007 - Elsevier
This review summarizes studies that attempted to determine the subtypes of nicotinic
acetylcholine receptors (nAChR) expressed in the dopaminergic nerve terminals in the …
acetylcholine receptors (nAChR) expressed in the dopaminergic nerve terminals in the …
Habenular α5 nicotinic receptor subunit signalling controls nicotine intake
Genetic variation in CHRNA5, the gene encoding the α5 nicotinic acetylcholine receptor
subunit, increases vulnerability to tobacco addiction and lung cancer, but the underlying …
subunit, increases vulnerability to tobacco addiction and lung cancer, but the underlying …
Molecular and physiological diversity of nicotinic acetylcholine receptors in the midbrain dopaminergic nuclei
R Klink, A de Kerchove d'Exaerde, M Zoli… - Journal of …, 2001 - Soc Neuroscience
Nicotinic acetylcholine receptors (nAChRs) on dopaminergic (DA) and GABAergic (Gaba)
projection neurons of the substantia nigra (SN) and ventral tegmental area (VTA) are …
projection neurons of the substantia nigra (SN) and ventral tegmental area (VTA) are …
Chronic exposure to nicotine upregulates the human α4β2 nicotinic acetylcholine receptor function
B Buisson, D Bertrand - Journal of Neuroscience, 2001 - Soc Neuroscience
Widely expressed in the brain, the α4β2 nicotinic acetylcholine receptor (nAChR) is
proposed to play a major role in the mechanisms that lead to and maintain nicotine …
proposed to play a major role in the mechanisms that lead to and maintain nicotine …
Chronic nicotine cell specifically upregulates functional α4* nicotinic receptors: basis for both tolerance in midbrain and enhanced long-term potentiation in perforant …
R Nashmi, C Xiao, P Deshpande… - Journal of …, 2007 - Soc Neuroscience
Understanding effects of chronic nicotine requires identifying the neurons and synapses
whose responses to nicotine itself, and to endogenous acetylcholine, are altered by …
whose responses to nicotine itself, and to endogenous acetylcholine, are altered by …
Neuronal nicotinic acetylcholine receptor subunit knockout mice: physiological and behavioral phenotypes and possible clinical implications
MR Picciotto, BJ Caldarone, DH Brunzell… - Pharmacology & …, 2001 - Elsevier
Nicotinic acetylcholine receptors (nAChRs) in the muscle, autonomic ganglia, and brain are
targets for pharmacologically administered nicotine. Several of the subunits that combine to …
targets for pharmacologically administered nicotine. Several of the subunits that combine to …
Nicotinic agonists, antagonists, and modulators from natural sources
JW Daly - Cellular and molecular neurobiology, 2005 - Springer
Acetylcholine receptors were initially defined as nicotinic or muscarinic, based on selective
activation by two natural products, nicotine and muscarine. Several further nicotinic agonists …
activation by two natural products, nicotine and muscarine. Several further nicotinic agonists …
Assembly of α4β2 nicotinic acetylcholine receptors assessed with functional fluorescently labeled subunits: effects of localization, trafficking, and nicotine-induced …
R Nashmi, ME Dickinson, S McKinney… - Journal of …, 2003 - Soc Neuroscience
Fura-2 recording of Ca2+ influx was used to show that incubation in 1 μm nicotine (2-6 d)
upregulates several pharmacological components of acetylcholine (ACh) responses in …
upregulates several pharmacological components of acetylcholine (ACh) responses in …