[HTML][HTML] Non-alcoholic fatty liver disease and COVID-19: Harmless companions or disease intensifier?

CG Dietrich, A Geier, U Merle - World journal of gastroenterology, 2023 - ncbi.nlm.nih.gov
The pandemics of coronavirus disease 2019 (COVID-19) and non-alcoholic fatty liver
disease (NAFLD) coexist. Elevated liver function tests are frequent in COVID-19 and may …

Precision nutrition to reset virus-induced human metabolic reprogramming and dysregulation (HMRD) in long-COVID

AS Naidu, CK Wang, P Rao, F Mancini… - npj Science of …, 2024 - nature.com
Abstract SARS‐CoV‐2, the etiological agent of COVID-19, is devoid of any metabolic
capacity; therefore, it is critical for the viral pathogen to hijack host cellular metabolic …

Mild to moderate post-COVID-19 alters markers of lymphocyte activation, exhaustion, and immunometabolic responses that can be partially associated by physical …

BSA Silva, T Pereira, LG Minuzzi, CS Padilha… - Frontiers in …, 2023 - frontiersin.org
Aim This study aimed to evaluate if physical activity is associated with systemic and cellular
immunometabolic responses, in young adults after mild-to-moderate COVID-19 infection …

High-dose coenzyme Q10 therapy versus placebo in patients with post COVID-19 condition: a randomized, phase 2, crossover trial

KS Hansen, TH Mogensen, J Agergaard… - The Lancet Regional …, 2023 - thelancet.com
Summary Background Post COVID-19 condition (PCC) is defined as symptoms lasting more
than 12 weeks after developing COVID-19. Evidence of mitochondrial dysfunction has been …

[HTML][HTML] Dysfunctional purinergic signaling correlates with disease severity in COVID-19 patients

AJ Pietrobon, R Andrejew, RWA Custodio… - Frontiers in …, 2022 - frontiersin.org
Ectonucleotidases modulate inflammatory responses by balancing extracellular ATP and
adenosine (ADO) and might be involved in COVID-19 immunopathogenesis. Here, we …

Human brain microvascular endothelial cells exposure to SARS-CoV-2 leads to inflammatory activation through NF-κB non-canonical pathway and mitochondrial …

CS Motta, S Torices, BG da Rosa, AC Marcos… - Viruses, 2023 - mdpi.com
Neurological effects of COVID-19 and long-COVID-19, as well as neuroinvasion by SARS-
CoV-2, still pose several questions and are of both clinical and scientific relevance. We …

Endotoxin tolerance and low activation of TLR-4/NF-κB axis in monocytes of COVID-19 patients

GP Dorneles, PC Teixeira, A Peres… - Journal of Molecular …, 2023 - Springer
Higher endotoxin in the circulation may indicate a compromised state of host immune
response against coinfections in severe COVID-19 patients. We evaluated the inflammatory …

Inhalation of ACE2-expressing lung exosomes provides prophylactic protection against SARS-CoV-2

Z Wang, S Hu, KD Popowski, S Liu, D Zhu… - Nature …, 2024 - nature.com
Continued emergence of SARS-CoV-2 variants of concern that are capable of escaping
vaccine-induced immunity highlights the urgency of developing new COVID-19 therapeutics …

The role of cluster of differentiation 39 (CD39) and purinergic signaling pathway in viral infections

A Elsaghir, EMW El-Sabaa, AK Ahmed… - Pathogens, 2023 - mdpi.com
CD39 is a marker of immune cells such as lymphocytes and monocytes. The CD39/CD73
pathway hydrolyzes ATP into adenosine, which has a potent immunosuppressive effect …

Aberrant phenotype of circulating antigen presenting cells in giant cell arteritis and polymyalgia rheumatica

RD Reitsema, BC Hesselink, WH Abdulahad… - Frontiers in …, 2023 - frontiersin.org
Background Giant Cell Arteritis (GCA) and Polymyalgia Rheumatica (PMR) are overlapping
inflammatory diseases. Antigen-presenting cells (APCs), including monocytes and dendritic …