Terpene-based natural deep eutectic systems as efficient solvents to recover astaxanthin from brown crab shell residues

LA Rodrigues, CV Pereira, IC Leonardo… - ACS Sustainable …, 2020 - ACS Publications
The potential of natural deep eutectic systems (NADESs) to efficiently extract astaxanthin
(AXT) contained in crab shell wastes was evaluated. Different terpene-based mixtures were …

Therapeutic deep eutectic system of capric acid and menthol: Characterization and pharmaceutical application

F Al-Akayleh, HHM Ali, MM Ghareeb… - Journal of Drug Delivery …, 2019 - Elsevier
The work outlined herein describes an evaluation of a new green solvent working as a drug
solubility enhancer made up of a eutectic system comprising mixtures of capric acid and …

DES-based vortex-assisted liquid-liquid microextraction procedure developed for the determination of paraben preservatives in mouthwashes

A Dalmaz, SS Özak - Microchemical Journal, 2022 - Elsevier
A green deep eutectic solvent-based vortex-assisted liquid–liquid microextraction (DES-
VALLME) procedure for the determination of parabens in mouthwashes was developed …

Microparticles containing curcumin solid dispersion: stability, bioavailability and anti-inflammatory activity

CCC Teixeira, LM Mendonça, MM Bergamaschi… - AAPS …, 2016 - Springer
This work aimed at improving the solubility of curcumin by the preparation of spray-dried
ternary solid dispersions containing Gelucire® 50/13-Aerosil® and quantifying the resulting …

Biopharmaceutical understanding of excipient variability on drug apparent solubility based on drug physicochemical properties. Case study: Superdisintegrants

P Zarmpi, T Flanagan, E Meehan, J Mann, N Fotaki - The AAPS Journal, 2020 - Springer
The presence of different excipient types/brands in solid oral dosage forms may affect
product performance and drug bioavailability. Understanding the biopharmaceutical …

Green deep eutectic solvent assisted liquid–liquid microextraction procedure for Sunset Yellow dye in effervescent vitamin C tablets

A Dalmaz, S Sivrikaya Özak - Journal of the Iranian Chemical Society, 2022 - Springer
Extensive research has been carried out recently using green deep eutectic solvents
(DESs). In this study, a simple, low-cost, and at the same time high-efficiency, green …

Study on Sulfamethoxazole–Piperazine Salt: A Mechanistic Insight into Simultaneous Improvement of Physicochemical Properties

P Roy, S Chakraborty, N Pandey, N Kumari… - Molecular …, 2023 - ACS Publications
Multidrug salts represent more than one drug in a crystal lattice and thus could be used to
deliver multiple drugs in a single dose. It showcases unique physicochemical properties in …

Supersaturating drug delivery system of fixed drug combination: sulfamethoxazole and trimethoprim

C Mendes, G Valentini… - Expert review of anti …, 2019 - Taylor & Francis
Background: The drug supersaturation in the intestinal lumen for few hours could result in
high bioavailability. The goal of this study was the development of a supersaturating drug …

Solubility of sulfanilamide in binary solvents containing water: Measurements and prediction using Buchowski-Ksiazczak solubility model

T Jeliński, N Bugalska, K Koszucka, M Przybyłek… - Journal of Molecular …, 2020 - Elsevier
The solubility of Sulfanilamide in binary mixtures comprising water and five organic solvents
was studied at different temperatures using a spectrophotometric method. Additionally, the …

Amorphous and crystalline particulates: challenges and perspectives in drug delivery

H Al-Obaidi, M Majumder, F Bari - Current pharmaceutical …, 2017 - ingentaconnect.com
Crystalline and amorphous dispersions have been the focus of academic and industrial
research due to their potential role in formulating poorly water-soluble drugs. This review …