Real-time fluorescence imaging in intraoperative decision making for cancer surgery

LJ Lauwerends, PBAA van Driel, RJB de Jong… - The Lancet …, 2021 - thelancet.com
Fluorescence-guided surgery is an intraoperative optical imaging method that provides
surgeons with real-time guidance for the delineation of tumours. Currently, in phase 1 and 2 …

Intraoperative imaging technology to maximise extent of resection for glioma

MD Jenkinson, DG Barone, A Bryant… - Cochrane Database …, 2018 - cochranelibrary.com
Background Extent of resection is considered to be a prognostic factor in neuro‐oncology.
Intraoperative imaging technologies are designed to help achieve this goal. It is not clear …

[HTML][HTML] Intraoperative MRI versus 5-ALA in high-grade glioma resection: a network meta-analysis

D Golub, J Hyde, S Dogra, J Nicholson… - Journal of …, 2020 - thejns.org
OBJECTIVE High-grade gliomas (HGGs) continue to carry poor prognoses, and patient
outcomes depend heavily on the extent of resection (EOR). The utility of conventional image …

The effectiveness and cost-effectiveness of intraoperative imaging in high-grade glioma resection; a comparative review of intraoperative ALA, fluorescein, ultrasound …

MS Eljamel, SO Mahboob - Photodiagnosis and photodynamic therapy, 2016 - Elsevier
Background Surgical resection of high-grade gliomas (HGG) is standard therapy because it
imparts significant progression free (PFS) and overall survival (OS). However, HGG-tumor …

Analysis of factors affecting 5-ALA fluorescence intensity in visualizing glial tumor cells—Literature review

M Mazurek, D Szczepanek, A Orzyłowska… - International journal of …, 2022 - mdpi.com
Glial tumors are one of the most common lesions of the central nervous system. Despite the
implementation of appropriate treatment, the prognosis is not successful. As shown in the …

The cost-effectiveness of tumor-treating fields therapy in patients with newly diagnosed glioblastoma

F Bernard-Arnoux, M Lamure, F Ducray… - Neuro …, 2016 - academic.oup.com
Background There is strong concern about the costs associated with adding tumor-treating
fields (TTF) therapy to standard first-line treatment for glioblastoma (GBM). Hence, we aimed …

Use of 5-ALA fluorescence–guided surgery versus white-light conventional microsurgery for the resection of newly diagnosed glioblastomas (RESECT study): a …

T Picart, J Pallud, J Berthiller, C Dumot… - Journal of …, 2023 - thejns.org
OBJECTIVE Only one phase III prospective randomized study, published in 2006, has
assessed the performance of 5-aminolevulinic acid (5-ALA) fluorescence–guided surgery …

Surgical treatment of glioblastoma: State-of-the-art and future trends

AHA Sales, J Beck, O Schnell, C Fung, B Meyer… - Journal of Clinical …, 2022 - mdpi.com
Glioblastoma (GBM) is a highly aggressive disease and is associated with poor prognosis
despite treatment advances in recent years. Surgical resection of tumor remains the main …

Economic implications of the modern treatment paradigm of glioblastoma: an analysis of global cost estimates and their utility for cost assessment

NJ Goel, CE Bird, WH Hicks… - Journal of Medical …, 2021 - Taylor & Francis
Introduction Glioblastoma is the most common primary brain tumor in adults. Standard of
care includes maximal surgical resection of the tumor followed by concurrent chemotherapy …

Intraoperative imaging technology to maximise extent of resection for glioma: a network meta‐analysis

DM Fountain, A Bryant, DG Barone… - Cochrane Database …, 2021 - cochranelibrary.com
Background Multiple studies have identified the prognostic relevance of extent of resection
in the management of glioma. Different intraoperative technologies have emerged in recent …