[HTML][HTML] MicroRNAs in Alzheimer's disease: Potential diagnostic markers and therapeutic targets

S Liu, M Fan, Q Zheng, S Hao, L Yang, Q Xia… - Biomedicine & …, 2022 - Elsevier
Alzheimer's disease (AD) is the most common neurodegenerative disease, with cognitive
decline as the primary clinical feature. According to epidemiological statistics, 50 million …

Molecular and cellular mechanisms of cardiovascular disorders in diabetes

MS Shah, M Brownlee - Circulation research, 2016 - Am Heart Assoc
The clinical correlations linking diabetes mellitus with accelerated atherosclerosis,
cardiomyopathy, and increased post-myocardial infarction fatality rates are increasingly …

The war against heart failure: the Lancet lecture

E Braunwald - The Lancet, 2015 - thelancet.com
Heart failure is a global problem with an estimated prevalence of 38 million patients
worldwide, a number that is increasing with the ageing of the population. It is the most …

Cardiac-specific miRNA in cardiogenesis, heart function, and cardiac pathology (with focus on myocardial infarction)

DA Chistiakov, AN Orekhov, YV Bobryshev - Journal of molecular and …, 2016 - Elsevier
Abstract Cardiac miRNAs (miR-1, miR133a, miR-208a/b, and miR-499) are abundantly
expressed in the myocardium. They play a central role in cardiogenesis, heart function and …

microRNAs in cardiovascular diseases: current knowledge and the road ahead

G Condorelli, MVG Latronico, E Cavarretta - Journal of the American …, 2014 - jacc.org
Over the last few years, the field of microribonucleic acid (miRNA) in cardiovascular biology
and disease has expanded at an incredible pace. miRNAs are themselves part of a larger …

miRNA therapeutics: a new class of drugs with potential therapeutic applications in the heart

BC Bernardo, JYY Ooi, RCY Lin… - Future medicinal …, 2015 - Taylor & Francis
miRNAs are small non-coding RNAs (ncRNAs), which regulate gene expression. Here, the
authors describe the contribution of miRNAs to cardiac biology and disease. They discuss …

The transcardiac gradient of cardio‐microRNAs in the failing heart

FZ Marques, D Vizi, O Khammy… - European journal of …, 2016 - Wiley Online Library
Aims Differential microRNA expression in peripheral blood has been observed in patients
with heart failure, suggesting their value as potential biomarkers and likely contributors to …

MicroRNAs expression profiles in cardiovascular diseases

E Bronze-da-Rocha - BioMed research international, 2014 - Wiley Online Library
The current search for new markers of cardiovascular diseases (CVDs) is explained by the
high morbidity and mortality still observed in developed and developing countries due to …

Non-coding RNAs in cardiac remodeling and heart failure

R Kumarswamy, T Thum - Circulation research, 2013 - Am Heart Assoc
Heart failure is a leading cause of death in industrialized nations especially in an aging
population. The recent improvements in cardiac revascularization therapy reduced death …

let-7b suppresses apoptosis and autophagy of human mesenchymal stem cells transplanted into ischemia/reperfusion injured heart 7by targeting caspase-3

O Ham, SY Lee, CY Lee, JH Park, J Lee… - Stem cell research & …, 2015 - Springer
Abstract Introduction Mesenchymal stem cells (MSCs) have therapeutic potential for the
repair of myocardial injury. The efficacy of MSC therapy for myocardial regeneration mainly …